Literature DB >> 18024020

On the mechanism of reduced tabletability of granules prepared by roller compaction.

Changquan Calvin Sun.   

Abstract

In a recent paper published in this journal, authors were perplexed by their results seemingly conflicting with our earlier findings [Sun, C.C., Himmelspach, M.W., 2006. Reduced tabletability of roller compacted granules as a result of granule size enlargement. J. Pharm. Sci. 95, 200-206]. After carefully reviewing the two studies, we conclude that results in the two studies are actually consistent with each other.

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Year:  2007        PMID: 18024020     DOI: 10.1016/j.ijpharm.2007.10.002

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  1 in total

1.  Quality by design I: Application of failure mode effect analysis (FMEA) and Plackett-Burman design of experiments in the identification of "main factors" in the formulation and process design space for roller-compacted ciprofloxacin hydrochloride immediate-release tablets.

Authors:  Raafat Fahmy; Ravikanth Kona; Ramesh Dandu; Walter Xie; Gregg Claycamp; Stephen W Hoag
Journal:  AAPS PharmSciTech       Date:  2012-09-20       Impact factor: 3.246

  1 in total

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