OBJECTIVE: To optimize the management of patients with cancer in a single testis and azoospermia. DESIGN: Case report. SETTING: Reproductive biology department. PATIENT(S): Two male patients referred in an emergency context for gamete cryopreservation before castration for cancer in a single testis; the patients were azoospermic before any sterilizing treatment. INTERVENTION(S): Testicular sperm extraction (TESE) was carried out synchronously with orchiectomy, allowing the cryopreservation of testicular spermatozoa. MAIN OUTCOME MEASURE(S): One year after the end of the cancer treatment, thawed testicular spermatozoa were successfully used in an intracytoplasmic sperm injection procedure. A twin pregnancy was obtained, and a healthy boy and girl were born. CONCLUSION(S): TESE and cryopreservation could be offered to every patient with cancer in a single testis and azoospermia.
OBJECTIVE: To optimize the management of patients with cancer in a single testis and azoospermia. DESIGN: Case report. SETTING: Reproductive biology department. PATIENT(S): Two male patients referred in an emergency context for gamete cryopreservation before castration for cancer in a single testis; the patients were azoospermic before any sterilizing treatment. INTERVENTION(S): Testicular sperm extraction (TESE) was carried out synchronously with orchiectomy, allowing the cryopreservation of testicular spermatozoa. MAIN OUTCOME MEASURE(S): One year after the end of the cancer treatment, thawed testicular spermatozoa were successfully used in an intracytoplasmic sperm injection procedure. A twin pregnancy was obtained, and a healthy boy and girl were born. CONCLUSION(S): TESE and cryopreservation could be offered to every patient with cancer in a single testis and azoospermia.