Literature DB >> 18021345

4-Aminopyridine (fampridine) effectively treats amlodipine poisoning: a case report.

B Wilffert1, R J Boskma, P H J van der Voort, D R A Uges, E N van Roon, J R B J Brouwers.   

Abstract

A case of a serious poisoning with the calcium entry blocker amlodipine is described, which was treated effectively with 4-aminopyridine. Calcium is suggested as general treatment of poisoning with calcium entry blockers in many guidelines. The use of intravenous 4-aminopyridine is theoretically useful to treat poisoning from calcium entry blockers and was demonstrated in this case report.

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Year:  2007        PMID: 18021345     DOI: 10.1111/j.1365-2710.2007.00861.x

Source DB:  PubMed          Journal:  J Clin Pharm Ther        ISSN: 0269-4727            Impact factor:   2.512


  2 in total

1.  Potentiation of high voltage-activated calcium channels by 4-aminopyridine depends on subunit composition.

Authors:  Li Li; De-Pei Li; Shao-Rui Chen; Jinjun Chen; Hongzhen Hu; Hui-Lin Pan
Journal:  Mol Pharmacol       Date:  2014-09-29       Impact factor: 4.436

Review 2.  4-aminopyridine toxicity: a case report and review of the literature.

Authors:  Andrew M King; Nathan B Menke; Kenneth D Katz; Anthony F Pizon
Journal:  J Med Toxicol       Date:  2012-09
  2 in total

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