| Literature DB >> 18020906 |
Abstract
This review briefly handles the use of (1)H NMR spectroscopy in lipoprotein subclass analytics. Potential diagnostic uses of (1)H NMR metabonomics of human serum for coronary heart disease, diabetic nephropathy and cancer are also discussed. In addition, miscellaneous recent applications of NMR metabonomics (e.g., a pharmacometabonomic tactic to personalize drug treatment) as well as multi-organ, multispecies and multi-omics approaches to molecular systems biology are featured. Some related experimental and data analysis methodologies are briefly introduced with respect to the biochemical rationales. Critical considerations on the potential diagnostic value of in vitro (1)H NMR are presented together with optimism toward the usage of body fluid (1)H NMR metabonomics in disease risk assessment and as an aid for personalized medicine.Entities:
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Year: 2007 PMID： 18020906 DOI： 10.1586/14737159.7.6.761
Source DB: PubMed Journal: Expert Rev Mol Diagn ISSN： 1473-7159 Impact factor: 5.225