| Literature DB >> 18020345 |
Frederic Menard1, Christian Frederik Weise, Mark Lautens.
Abstract
A catalytic desymmetrization of strained alkenes by ring-opening of meso-diazabicycles with acyl anion nucleophiles is reported. Densely functionalized trans-1,2-hydrazinoacyl cyclopentene building blocks are obtained stereoselectively. The acyl anion equivalent is generated in situ under very mild conditions from readily available organoboron precursors.Entities:
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Year: 2007 PMID： 18020345 DOI： 10.1021/ol7022054
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005