| Literature DB >> 18019527 |
Hélène Bertrand1, David Monchaud, Anne De Cian, Régis Guillot, Jean-Louis Mergny, Marie-Paule Teulade-Fichou.
Abstract
A family of terpyridine metallo-organic complexes has been designed and its recognition properties of G-quadruplex-DNA investigated. The series combines easy synthetic access and good affinity-selectivity ratio for quadruplex-DNA. Our study also highlights that the geometry of the metal center strongly governs the ability of the compounds to discriminate quadruplex from duplex-DNA.Entities:
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Year: 2007 PMID: 18019527 DOI: 10.1039/b708635k
Source DB: PubMed Journal: Org Biomol Chem ISSN: 1477-0520 Impact factor: 3.876