Literature DB >> 18019527

The importance of metal geometry in the recognition of G-quadruplex-DNA by metal-terpyridine complexes.

Hélène Bertrand1, David Monchaud, Anne De Cian, Régis Guillot, Jean-Louis Mergny, Marie-Paule Teulade-Fichou.   

Abstract

A family of terpyridine metallo-organic complexes has been designed and its recognition properties of G-quadruplex-DNA investigated. The series combines easy synthetic access and good affinity-selectivity ratio for quadruplex-DNA. Our study also highlights that the geometry of the metal center strongly governs the ability of the compounds to discriminate quadruplex from duplex-DNA.

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Year:  2007        PMID: 18019527     DOI: 10.1039/b708635k

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN: 1477-0520            Impact factor:   3.876


  16 in total

Review 1.  Application of metal coordination chemistry to explore and manipulate cell biology.

Authors:  Kathryn L Haas; Katherine J Franz
Journal:  Chem Rev       Date:  2009-10       Impact factor: 60.622

2.  Synthesis, characterization, and DNA binding of a novel ligand and its Cu (II) complex.

Authors:  Mei-Jin Li; Tao-Yu Lan; Zhi-Shan Lin; Changqing Yi; Guo-Nan Chen
Journal:  J Biol Inorg Chem       Date:  2013-12       Impact factor: 3.358

3.  Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy.

Authors:  Hee-Sheung Lee; Mar Carmena; Mikhail Liskovykh; Emma Peat; Jung-Hyun Kim; Mitsuo Oshimura; Hiroshi Masumoto; Marie-Paule Teulade-Fichou; Yves Pommier; William C Earnshaw; Vladimir Larionov; Natalay Kouprina
Journal:  Cancer Res       Date:  2018-08-30       Impact factor: 12.701

4.  Synthesis, characterization and biological evaluation of six highly cytotoxic ruthenium(ii) complexes with 4'-substituted-2,2':6',2''-terpyridine.

Authors:  Qi-Pin Qin; Ting Meng; Ming-Xiong Tan; Yan-Cheng Liu; Shu-Long Wang; Bi-Qun Zou; Hong Liang
Journal:  Medchemcomm       Date:  2018-02-02       Impact factor: 3.597

5.  Aqua-[4'-(4-chloro-phen-yl)-2,2':6',2''-terpyridine]-nitratocopper(II) nitrate [4'-(4-chloro-phen-yl)-2,2':6',2''-terpyridine]-dinitratocopper(II) monohydrate.

Authors:  Juan Zhao; Shuo Shi; Tianming Yao; Zhongfei Tan
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2011-02-19

6.  Targeting human telomeric G-quadruplex DNA and inhibition of telomerase activity with [(dmb)2Ru(obip)Ru(dmb)2](4+).

Authors:  Shuo Shi; Shane Gao; Tongcheng Cao; Jie Liu; Xing Gao; Jian Hao; Chunyan Lv; Hailiang Huang; Jun Xu; Tianming Yao
Journal:  PLoS One       Date:  2013-12-27       Impact factor: 3.240

7.  Effect of G-quadruplex polymorphism on the recognition of telomeric DNA by a metal complex.

Authors:  Caterina Musetti; A Paul Krapcho; Manlio Palumbo; Claudia Sissi
Journal:  PLoS One       Date:  2013-03-13       Impact factor: 3.240

8.  Chiral metallo-supramolecular complexes selectively recognize human telomeric G-quadruplex DNA.

Authors:  Haijia Yu; Xiaohui Wang; Manliang Fu; Jinsong Ren; Xiaogang Qu
Journal:  Nucleic Acids Res       Date:  2008-09-06       Impact factor: 16.971

9.  Highly efficient radiosensitization of human glioblastoma and lung cancer cells by a G-quadruplex DNA binding compound.

Authors:  Patrick Merle; Marine Gueugneau; Marie-Paule Teulade-Fichou; Mélanie Müller-Barthélémy; Simon Amiard; Emmanuel Chautard; Corinne Guetta; Véronique Dedieu; Yves Communal; Jean-Louis Mergny; Maria Gallego; Charles White; Pierre Verrelle; Andreï Tchirkov
Journal:  Sci Rep       Date:  2015-11-06       Impact factor: 4.379

10.  Terpyridine-Cu(ii) targeting human telomeric DNA to produce highly stereospecific G-quadruplex DNA metalloenzyme.

Authors:  Yinghao Li; Mingpan Cheng; Jingya Hao; Changhao Wang; Guoqing Jia; Can Li
Journal:  Chem Sci       Date:  2015-06-24       Impact factor: 9.825

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