Literature DB >> 18007429

Preparation of new 2,3-diphenylpropenoic acid esters - good yields even for the more hindered Z isomers.

László Boros1, Károly Felföldi, István Pálinkó.   

Abstract

The potassium salt of E- and Z-2,3-diphenylpropenoic acids prepared in situ could be esterified efficiently in DMSO with the appropriate alkyl halides at room temperature. In this way 10 previously undescribed esters of these acids were synthesised and characterised. Excellent yields were observed for most of the E isomers and the more hindered Z esters were also obtained in good yields, far better than those obtained applying the classical acid-catalysed esterification reaction.

Entities:  

Mesh:

Substances:

Year:  2004        PMID: 18007429      PMCID: PMC6147297          DOI: 10.3390/90400256

Source DB:  PubMed          Journal:  Molecules        ISSN: 1420-3049            Impact factor:   4.411


  1 in total

1.  Synthesis, antimuscarinic activity and quantitative structure-activity relationship (QSAR) of tropinyl and piperidinyl esters.

Authors:  R Xu; M K Sim; M L Go
Journal:  Chem Pharm Bull (Tokyo)       Date:  1998-02       Impact factor: 1.645

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.