Literature DB >> 18007419

The synthesis of dicationic extended bis-benzimidazoles.

Zhijan Kang1, Christine C Dykstra, David W Boykin.   

Abstract

The synthesis of extended dicationic bis-benzimidazoles starting from trans-1,2-bis(4-cyanophenyl)ethene and trans-1,2-bis(4-cyanophenyl)cyclopropane is reported. The target diamidines show significant in vitro activity against B. subtilis.

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Year:  2004        PMID： 18007419      PMCID： PMC6147318          DOI： 10.3390/90300158

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  8 in total

1.  Activity of cationically substituted bis-benzimidazoles against experimental Pneumocystis carinii pneumonia.

Authors:  R R Tidwell; S K Jones; N A Naiman; L C Berger; W B Brake; C C Dykstra; J E Hall
Journal:  Antimicrob Agents Chemother       Date:  1993-08       Impact factor: 5.191

2.  Synthesis and antiprotozoal activity of aza-analogues of furamidine.

Authors:  Mohamed A Ismail; Reto Brun; Judy D Easterbrook; Farial A Tanious; W David Wilson; David W Boykin
Journal:  J Med Chem       Date:  2003-10-23       Impact factor: 7.446

3.  [Polynuclear thiophenes. 8. Trypanocidal diamidines of 2-phenyl-thionaphthene].

Authors:  O Dann; E Hieke; H Hahn; H H Miserre; G Lürding; R Rössler
Journal:  Justus Liebigs Ann Chem       Date:  1970

4.  Extended aromatic furan amidino derivatives as anti-Pneumocystis carinii agents.

Authors:  K T Hopkins; W D Wilson; B C Bender; D R McCurdy; J E Hall; R R Tidwell; A Kumar; M Bajic; D W Boykin
Journal:  J Med Chem       Date:  1998-09-24       Impact factor: 7.446

5.  Detection of inhibition of bovine viral diarrhea virus by aromatic cationic molecules.

Authors:  M Daniel Givens; Christine C Dykstra; Kenny V Brock; David A Stringfellow; Arvind Kumar; Chad E Stephens; Hakan Goker; David W Boykin
Journal:  Antimicrob Agents Chemother       Date:  2003-07       Impact factor: 5.191

6.  In vitro antifungal activities of a series of dication-substituted carbazoles, furans, and benzimidazoles.

Authors:  M Del Poeta; W A Schell; C C Dykstra; S K Jones; R R Tidwell; A Kumar; D W Boykin; J R Perfect
Journal:  Antimicrob Agents Chemother       Date:  1998-10       Impact factor: 5.191

7.  Structure-in vitro activity relationships of pentamidine analogues and dication-substituted bis-benzimidazoles as new antifungal agents.

Authors:  M Del Poeta; W A Schell; C C Dykstra; S Jones; R R Tidwell; A Czarny; M Bajic; A Kumar; D Boykin; J R Perfect
Journal:  Antimicrob Agents Chemother       Date:  1998-10       Impact factor: 5.191

8.  Structure, DNA minor groove binding, and base pair specificity of alkyl- and aryl-linked bis(amidinobenzimidazoles) and bis(amidinoindoles).

Authors:  T A Fairley; R R Tidwell; I Donkor; N A Naiman; K A Ohemeng; R J Lombardy; J A Bentley; M Cory
Journal:  J Med Chem       Date:  1993-06-11       Impact factor: 7.446
  8 in total

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