Literature DB >> 18007127

Menorrhagia and bleeding disorders.

Ihab El-Hemaidi1, Amer Gharaibeh, Hassan Shehata.   

Abstract

PURPOSE OF REVIEW: Menorrhagia affects 30% of women in reproductive age. Once referred to a gynaecologist, possible causative bleeding disorders are not routinely investigated and the risk of surgical intervention is high. This may lead to an increase in surgical complications and a negative health and psychological impact on women as well as an unnecessary financial burden on the health service. RECENT
FINDINGS: Although the estimated community prevalence of bleeding disorders is 2%, these disorders are consistently reported to affect 10-20% of women with objectively documented menorrhagia and to be even higher in adolescents. Recently, underlying bleeding disorders, particularly von Willebrand's disease and platelet function disorders, have been found to be prevalent in women with menorrhagia. This article critically appraises the current literature in this field.
SUMMARY: In the UK, 20% of all women, and 30% in the USA, have a hysterectomy before the age of 60; menorrhagia is the main presenting problem in at least 50-70%. In approximately 50% of cases, no organic pathology is determined, and dysfunctional uterine bleeding is diagnosed. Diagnosis and management of bleeding disorders may possibly reduce the need for surgical intervention, leading to a positive impact on women and the health service.

Entities:  

Mesh:

Year:  2007        PMID: 18007127     DOI: 10.1097/GCO.0b013e3282f1ddbe

Source DB:  PubMed          Journal:  Curr Opin Obstet Gynecol        ISSN: 1040-872X            Impact factor:   1.927


  14 in total

Review 1.  Challenges in the gynecologic care of premenopausal women with breast cancer.

Authors:  Jamie N Bakkum-Gamez; Shannon K Laughlin; Jani R Jensen; Clement O Akogyeram; Sandhya Pruthi
Journal:  Mayo Clin Proc       Date:  2011-02-09       Impact factor: 7.616

2.  Negative attitudes and affect do not predict elective hysterectomy: a prospective analysis from the Study of Women's Health Across the Nation.

Authors:  Carolyn J Gibson; Joyce T Bromberger; Gerson E Weiss; Rebecca C Thurston; MaryFran Sowers; Karen A Matthews
Journal:  Menopause       Date:  2011-05       Impact factor: 2.953

Review 3.  Non-surgical interventions for treating heavy menstrual bleeding (menorrhagia) in women with bleeding disorders.

Authors:  Sujoy Ray; Amita Ray
Journal:  Cochrane Database Syst Rev       Date:  2016-11-10

4.  Therapy of heavy menstrual bleeding in Korea: Subanalysis and results from a multinational clinical trial in the Asian region investigating the levonorgestrel-releasing intrauterine system versus conventional therapy.

Authors:  Byung Seok Lee; Xu Ling; Shaheena Asif; Peter Kraemer; Jens Ulrich Hanisch; Pirjo Inki; Jung Eun Lee
Journal:  Obstet Gynecol Sci       Date:  2015-03-16

5.  Changes in cardiovascular risk factors by hysterectomy status with and without oophorectomy: Study of Women's Health Across the Nation.

Authors:  Karen A Matthews; Carolyn J Gibson; Samar R El Khoudary; Rebecca C Thurston
Journal:  J Am Coll Cardiol       Date:  2013-05-15       Impact factor: 24.094

6.  Pattern of mental ill health morbidities following hysterectomy for benign gynaecological disorders among Nigerian women.

Authors:  Michael A Okunlola; Celestine Umuerri; Olayinka O Omigbodun; Imran O Morhason-Bello; Stella N Okonkwo; Oladosu A Ojengbede
Journal:  Int J Ment Health Syst       Date:  2009-07-30

7.  Pre-endoscopic screening for Helicobacter pylori and celiac disease in young anemic women.

Authors:  Lucy Vannella; Debora Gianni; Edith Lahner; Antonio Amato; Enzo Grossi; Gianfranco Delle Fave; Bruno Annibale
Journal:  World J Gastroenterol       Date:  2009-06-14       Impact factor: 5.742

Review 8.  Antifibrinolytics for heavy menstrual bleeding.

Authors:  Alison C Bryant-Smith; Anne Lethaby; Cindy Farquhar; Martha Hickey
Journal:  Cochrane Database Syst Rev       Date:  2018-04-15

9.  Unnecessary Hysterectomy due to Menorrhagia and Disorders of Hemostasis: An Example of Overuse and Excessive Demand for Medical Services.

Authors:  Svetlana M Djukic; Danijela Lekovic; Nikola Jovic; Mirjana Varjacic
Journal:  Front Pharmacol       Date:  2016-12-23       Impact factor: 5.810

10.  Body mass index following natural menopause and hysterectomy with and without bilateral oophorectomy.

Authors:  C J Gibson; R C Thurston; S R El Khoudary; K Sutton-Tyrrell; K A Matthews
Journal:  Int J Obes (Lond)       Date:  2012-09-25       Impact factor: 5.095

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