| Literature DB >> 18006306 |
Richard M Angell1, Paul Bamborough, Anne Cleasby, Stuart G Cockerill, Katherine L Jones, Christopher J Mooney, Donald O Somers, Ann L Walker.
Abstract
The biphenyl amides (BPAs) are a novel series of p38 MAP kinase inhibitors. The discovery of the series through structure-based focused screening is described, and the binding mode of the compounds is explained with reference to X-ray crystal structures.Entities:
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Year: 2007 PMID： 18006306 DOI： 10.1016/j.bmcl.2007.10.076
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823