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Literature DB >> 18003717

Insulin-like growth factor-binding proteins and bone metabolism.

Abstract

Insulin-like growth factor-binding proteins (IGFBPs) are important regulators of bone metabolism. However, their precise roles are not fully understood, since IGFBPs can have both enhancing and inhibiting effects on IGF action, depending on context and posttranslational modifications, as well as IGF-independent effects. This review focuses on recent findings from cell culture, rodent models, and clinical studies concerning local IGFBP-2, IGFBP-4, and IGFBP-5 action in bone.

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Year: 2007 PMID： 18003717 DOI： 10.1152/ajpendo.00648.2007

Source DB: PubMed Journal: Am J Physiol Endocrinol Metab ISSN： 0193-1849 Impact factor: 4.310

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Cited

25 in total

Review 1. Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up.

Authors: Alberto Roselló-Díez; Alexandra L Joyner
Journal: Endocr Rev Date: 2015-10-20 Impact factor: 19.871

2. Nuclear factor I transcription factors regulate IGF binding protein 5 gene transcription in human osteoblasts.

Authors: Laura A Pérez-Casellas; Xiaoying Wang; Kristy D Howard; Mark W Rehage; Donna D Strong; Thomas A Linkhart
Journal: Biochim Biophys Acta Date: 2008-09-10

3. Defining the disulfide bonds of insulin-like growth factor-binding protein-5 by tandem mass spectrometry with electron transfer dissociation and collision-induced dissociation.

Authors: Mahta Nili; Aditi Mukherjee; Ujwal Shinde; Larry David; Peter Rotwein
Journal: J Biol Chem Date: 2011-11-22 Impact factor: 5.157

Review 4. IGF-I/IGFBP system: metabolism outline and physical exercise.

Authors: R Gatti; E F De Palo; G Antonelli; P Spinella
Journal: J Endocrinol Invest Date: 2012-06-18 Impact factor: 4.256

5. A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma.

Authors: Lisa Mirabello; Roelof Koster; Branden S Moriarity; Logan G Spector; Paul S Meltzer; Joy Gary; Mitchell J Machiela; Nathan Pankratz; Orestis A Panagiotou; David Largaespada; Zhaoming Wang; Julie M Gastier-Foster; Richard Gorlick; Chand Khanna; Silvia Regina Caminada de Toledo; Antonio S Petrilli; Ana Patiño-Garcia; Luis Sierrasesúmaga; Fernando Lecanda; Irene L Andrulis; Jay S Wunder; Nalan Gokgoz; Massimo Serra; Claudia Hattinger; Piero Picci; Katia Scotlandi; Adrienne M Flanagan; Roberto Tirabosco; Maria Fernanda Amary; Dina Halai; Mandy L Ballinger; David M Thomas; Sean Davis; Donald A Barkauskas; Neyssa Marina; Lee Helman; George M Otto; Kelsie L Becklin; Natalie K Wolf; Madison T Weg; Margaret Tucker; Sholom Wacholder; Joseph F Fraumeni; Neil E Caporaso; Joseph F Boland; Belynda D Hicks; Aurelie Vogt; Laurie Burdett; Meredith Yeager; Robert N Hoover; Stephen J Chanock; Sharon A Savage
Journal: Cancer Discov Date: 2015-06-17 Impact factor: 39.397

6. Insulin-like growth factor-binding protein-5 inhibits osteoblast differentiation and skeletal growth by blocking insulin-like growth factor actions.

Authors: Aditi Mukherjee; Peter Rotwein
Journal: Mol Endocrinol Date: 2008-02-21

Insulin-like growth factor-binding proteins and bone metabolism.

Review 1. Regulation of Long Bone Growth in Vertebrates; It Is Time to Catch Up.

2. Nuclear factor I transcription factors regulate IGF binding protein 5 gene transcription in human osteoblasts.

3. Defining the disulfide bonds of insulin-like growth factor-binding protein-5 by tandem mass spectrometry with electron transfer dissociation and collision-induced dissociation.

Review 4. IGF-I/IGFBP system: metabolism outline and physical exercise.

5. A Genome-Wide Scan Identifies Variants in NFIB Associated with Metastasis in Patients with Osteosarcoma.

6. Insulin-like growth factor-binding protein-5 inhibits osteoblast differentiation and skeletal growth by blocking insulin-like growth factor actions.

7. Gender-specific changes in bone turnover and skeletal architecture in igfbp-2-null mice.

8. Igfbp2 Deletion in Ovariectomized Mice Enhances Energy Expenditure but Accelerates Bone Loss.

9. Adsorbed fibrinogen enhances production of bone- and angiogenic-related factors by monocytes/macrophages.

Review 10. IGF-binding protein 2 is a candidate target of therapeutic potential in cancer.