Literature DB >> 18003645

Kernel approaches for genic interaction extraction.

Seonho Kim1, Juntae Yoon, Jihoon Yang.   

Abstract

MOTIVATION: Automatic knowledge discovery and efficient information access such as named entity recognition and relation extraction between entities have recently become critical issues in the biomedical literature. However, the inherent difficulty of the relation extraction task, mainly caused by the diversity of natural language, is further compounded in the biomedical domain because biomedical sentences are commonly long and complex. In addition, relation extraction often involves modeling long range dependencies, discontiguous word patterns and semantic relations for which the pattern-based methodology is not directly applicable.
RESULTS: In this article, we shift the focus of biomedical relation extraction from the problem of pattern extraction to the problem of kernel construction. We suggest four kernels: predicate, walk, dependency and hybrid kernels to adequately encapsulate information required for a relation prediction based on the sentential structures involved in two entities. For this purpose, we view the dependency structure of a sentence as a graph, which allows the system to deal with an essential one from the complex syntactic structure by finding the shortest path between entities. The kernels we suggest are augmented gradually from the flat features descriptions to the structural descriptions of the shortest paths. As a result, we obtain a very promising result, a 77.5 F-score with the walk kernel on the Language Learning in Logic (LLL) 05 genic interaction shared task. AVAILABILITY: The used algorithms are free for use for academic research and are available from our Web site http://mllab.sogang.ac.kr/ approximately shkim/LLL05.tar.gz.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 18003645     DOI: 10.1093/bioinformatics/btm544

Source DB:  PubMed          Journal:  Bioinformatics        ISSN: 1367-4803            Impact factor:   6.937


  21 in total

1.  Bridging semantics and syntax with graph algorithms-state-of-the-art of extracting biomedical relations.

Authors:  Yuan Luo; Özlem Uzuner; Peter Szolovits
Journal:  Brief Bioinform       Date:  2016-02-05       Impact factor: 11.622

2.  Bayesian inference of protein-protein interactions from biological literature.

Authors:  Rajesh Chowdhary; Jinfeng Zhang; Jun S Liu
Journal:  Bioinformatics       Date:  2009-04-15       Impact factor: 6.937

3.  Extracting causal relations on HIV drug resistance from literature.

Authors:  Quoc-Chinh Bui; Breanndán O Nualláin; Charles A Boucher; Peter M A Sloot
Journal:  BMC Bioinformatics       Date:  2010-02-23       Impact factor: 3.169

4.  Walk-weighted subsequence kernels for protein-protein interaction extraction.

Authors:  Seonho Kim; Juntae Yoon; Jihoon Yang; Seog Park
Journal:  BMC Bioinformatics       Date:  2010-02-25       Impact factor: 3.169

5.  A comprehensive benchmark of kernel methods to extract protein-protein interactions from literature.

Authors:  Domonkos Tikk; Philippe Thomas; Peter Palaga; Jörg Hakenberg; Ulf Leser
Journal:  PLoS Comput Biol       Date:  2010-07-01       Impact factor: 4.475

6.  Extracting relations from traditional Chinese medicine literature via heterogeneous entity networks.

Authors:  Huaiyu Wan; Marie-Francine Moens; Walter Luyten; Xuezhong Zhou; Qiaozhu Mei; Lu Liu; Jie Tang
Journal:  J Am Med Inform Assoc       Date:  2015-07-29       Impact factor: 4.497

Review 7.  Recent advances in biomedical literature mining.

Authors:  Sendong Zhao; Chang Su; Zhiyong Lu; Fei Wang
Journal:  Brief Bioinform       Date:  2021-05-20       Impact factor: 11.622

8.  Linguistic feature analysis for protein interaction extraction.

Authors:  Timur Fayruzov; Martine De Cock; Chris Cornelis; Veronique Hoste
Journal:  BMC Bioinformatics       Date:  2009-11-12       Impact factor: 3.169

9.  A detailed error analysis of 13 kernel methods for protein-protein interaction extraction.

Authors:  Domonkos Tikk; Illés Solt; Philippe Thomas; Ulf Leser
Journal:  BMC Bioinformatics       Date:  2013-01-16       Impact factor: 3.169

10.  Extracting drug-drug interaction from the biomedical literature using a stacked generalization-based approach.

Authors:  Linna He; Zhihao Yang; Zhehuan Zhao; Hongfei Lin; Yanpeng Li
Journal:  PLoS One       Date:  2013-06-13       Impact factor: 3.240

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.