Literature DB >> 17999533

gem-Dibromomethylarenes: a convenient substitute for noncommercial aldehydes in the knoevenagel-doebner reaction for the synthesis of alpha,beta-unsaturated carboxylic acids.

John Kallikat Augustine1, Yanjerappa Arthoba Naik, Ashis Baran Mandal, Nagaraja Chowdappa, Vinuthan B Praveen.   

Abstract

A facile synthesis of alpha,beta-unsaturated carboxylic acids from gem-dibromomethylarenes is described. gem-Dibromomethylarenes are employed for the first time in the Knoevenagel-Doebner reaction as aldehyde equivalents for the efficient synthesis of alpha,beta-unsaturated carboxylic acids.

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Year:  2007        PMID: 17999533     DOI: 10.1021/jo701888m

Source DB:  PubMed          Journal:  J Org Chem        ISSN: 0022-3263            Impact factor:   4.354


  3 in total

1.  1-Dibromo-methyl-4-meth-oxy-2-nitro-benzene.

Authors:  Hoong-Kun Fun; Jia Hao Goh; B Chandrakantha; Arun M Isloor
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2009-08-19

2.  Synthesis of functionalized benzo[1,3]dioxin-4-ones from salicylic acid and acetylenic esters and their direct amidation.

Authors:  Rasmi P Bhaskaran; Kalinga H Nayak; Beneesh P Babu
Journal:  RSC Adv       Date:  2021-07-13       Impact factor: 4.036

3.  Functionalized Nylon 6 Fabric as an Efficient and Recyclable Catalyst for Knoevenagel Condensation.

Authors:  Zhong Yan; Yuwei Liu; Wenwen Wang; Dong Wang
Journal:  ACS Omega       Date:  2022-09-06
  3 in total

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