Literature DB >> 17996699

AROuSing SIRT1: identification of a novel endogenous SIRT1 activator.

Eric Verdin1.   

Abstract

SIRT1 is a protein deacetylase that regulates cellular responses to a variety of stresses. In a recent issue of Molecular Cell, Kim et al. (2007) report the identification of a cellular protein, AROS, that activates the SIRT1-mediated deacetylation of p53.

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Year:  2007        PMID: 17996699     DOI: 10.1016/j.molcel.2007.10.013

Source DB:  PubMed          Journal:  Mol Cell        ISSN: 1097-2765            Impact factor:   17.970


  6 in total

1.  Respected Sir(2): magic target for diabetes.

Authors:  Pratibha V Nerurkar; Vivek R Nerurkar
Journal:  Cellscience       Date:  2008-04-27

2.  Role of p53 in the anti-proliferative effects of Sirt1 inhibition in prostate cancer cells.

Authors:  Brittney Jung-Hynes; Nihal Ahmad
Journal:  Cell Cycle       Date:  2009-05-13       Impact factor: 4.534

3.  Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells.

Authors:  Basant Kumar Thakur; Tino Dittrich; Prakash Chandra; Annette Becker; Wolfgang Kuehnau; Jan-Henning Klusmann; Dirk Reinhardt; Karl Welte
Journal:  Int J Cancer       Date:  2012-08-12       Impact factor: 7.396

4.  Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.

Authors:  Madhavi Annamanedi; Arunasree M Kalle
Journal:  PLoS One       Date:  2014-06-20       Impact factor: 3.240

5.  Opposing effects of sirtuins on neuronal survival: SIRT1-mediated neuroprotection is independent of its deacetylase activity.

Authors:  Jason A Pfister; Chi Ma; Brad E Morrison; Santosh R D'Mello
Journal:  PLoS One       Date:  2008-12-31       Impact factor: 3.240

6.  Change in plasma sirtuin 1 level by injection into uterus of resveratrol in Korean cattle.

Authors:  Dae Hyun Kim; Jun Koo Yi; Jae Jung Ha; Dong Yep Oh; Do Yeoung Kim; Yoon Seok Lee
Journal:  Anim Reprod       Date:  2020-03-17       Impact factor: 1.807

  6 in total

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