Literature DB >> 17996582

Urinary leukotriene E4.

Nathan Rabinovitch1.   

Abstract

Measurement of urinary leukotriene E4 (LTE4) is a sensitive and noninvasive method of assaying total body cysteinyl leukotriene production and changes in cysteinyl leukotriene levels in specific microenvironments, such as the airway. Urinary LTE4 measurements can be used as sensitive biomarkers of exposure to asthma triggers, such as air pollution and viral infections. Recent studies suggest the potential of using urinary LTE4 concentrations as predictors of asthma control and markers of susceptibility to treatment with leukotriene receptor antagonists.

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Year:  2007        PMID： 17996582     DOI： 10.1016/j.iac.2007.09.004

Source DB:  PubMed          Journal:  Immunol Allergy Clin North Am        ISSN： 0889-8561            Impact factor:   3.479


  8 in total

1.  Elevated levels of leukotriene C4 synthase mRNA distinguish a subpopulation of eosinophilic oesophagitis patients.

Authors:  W S Lexmond; M Pardo; K Rooney; J A Goettel; S B Snapper; E H Yen; E Dehlink; S Nurko; E Fiebiger
Journal:  Clin Exp Allergy       Date:  2013-08       Impact factor: 5.018

2.  Urinary leukotriene E4, obesity, and adenotonsillar hypertrophy in Chinese children with sleep disordered breathing.

Authors:  Yuelin Shen; Zhifei Xu; Kunling Shen
Journal:  Sleep       Date:  2011-08-01       Impact factor: 5.849

Review 3.  Measures of asthma control.

Authors:  Christian Bime; Jessica Nguyen; Robert A Wise
Journal:  Curr Opin Pulm Med       Date:  2012-01       Impact factor: 3.155

4.  A simple and robust UPLC-SRM/MS method to quantify urinary eicosanoids.

Authors:  Katharina Sterz; Gerhard Scherer; Josef Ecker
Journal:  J Lipid Res       Date:  2012-02-14       Impact factor: 5.922

5.  ALOX5 polymorphism associates with increased leukotriene production and reduced lung function and asthma control in children with poorly controlled asthma.

Authors:  E Mougey; J E Lang; H Allayee; W G Teague; A J Dozor; R A Wise; J J Lima
Journal:  Clin Exp Allergy       Date:  2013-05       Impact factor: 5.018

6.  Leukotriene-E4 in human urine: Comparison of on-line purification and liquid chromatography-tandem mass spectrometry to affinity purification followed by enzyme immunoassay.

Authors:  Michael Armstrong; Andrew H Liu; Ronald Harbeck; Rick Reisdorph; Nathan Rabinovitch; Nichole Reisdorph
Journal:  J Chromatogr B Analyt Technol Biomed Life Sci       Date:  2009-08-18       Impact factor: 3.205

7.  Asthma in sickle cell disease: implications for treatment.

Authors:  Kathryn Blake; John Lima
Journal:  Anemia       Date:  2011-03-03

Review 8.  Role of biomarkers in understanding and treating children with asthma: towards personalized care.

Authors:  Jason E Lang; Kathryn V Blake
Journal:  Pharmgenomics Pers Med       Date:  2013-08-21
  8 in total

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