Literature DB >> 17993046

For individuals with obstructive sleep apnea, institution of CPAP therapy is associated with an amelioration of symptoms of depression which is sustained long term.

Daniel J Schwartz1, Gillian Karatinos.   

Abstract

OBJECTIVE: To assess the sustainability of an improvement in symptoms of depression using CPAP therapy in patients with obstructive sleep apnea. PATIENTS/
METHODS: Patients referred to our center for evaluation of obstructive sleep apnea who had a respiratory disturbance index (RDI) of > or =15 and who demonstrated a significant response to CPAP (50% or greater drop in RDI), were evaluated for symptoms of depression using the Beck Depression Inventory-Fast Screen for Medical Patients (BDI). These individuals were asked to complete the BDI assessment again after 4 to 6 weeks of treatment with CPAP (short-term follow-up), and then reassessed approximately one year later (long-term follow-up).
RESULTS: In this group of patients, the institution of CPAP therapy resulted in a significant decrease in those symptoms of depression assessed by the BDI at both the short-term and long-term follow-up periods.
CONCLUSIONS: For patients with OSA who continue CPAP therapy, we noted a statistically significant, sustained improvement in those symptoms of depression measured by the BDI.

Entities:  

Mesh:

Year:  2007        PMID: 17993046      PMCID: PMC2045710     

Source DB:  PubMed          Journal:  J Clin Sleep Med        ISSN: 1550-9389            Impact factor:   4.062


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