Literature DB >> 17992077

What is it like to be vegetative or minimally conscious?

Steven Laureys1, Melanie Boly.   

Abstract

PURPOSE OF REVIEW: Patients in a vegetative or minimally conscious state continue to pose problems in terms of diagnosis, prognosis and treatment. Despite recent waves of international media attention following Terri Schiavo's death and the 'miracle recovery' of Terry Wallis, research efforts aimed at increasing our knowledge about brain function in these conditions remain scarce and must address a series of difficulties, including financial and ethical barriers. Here we review current possibilities and limitations of clinical and para-clinical assessment of chronic disorders of consciousness. RECENT
FINDINGS: During the past year the field has witnessed publication of significant, yet isolated, case reports in top-ranking journals, including Science and Nature. Such milestone reports and other impressive recent technological advances in the study of vegetative and minimally conscious patients reveal enthralling areas of science that must find their way to clinical medical reality.
SUMMARY: Consciousness is a subjective experience whose study has remained within the purview of philosophy for millennia. That has finally changed, and empirical evidence from functional neuroimaging offers a genuine glimpse at a solution to the infamous mind-body conundrum. New technological and scientific advances offer the neurological community unique ways to improve our understanding and management of vegetative and minimally conscious patients.

Entities:  

Mesh:

Year:  2007        PMID: 17992077     DOI: 10.1097/WCO.0b013e3282f1d6dd

Source DB:  PubMed          Journal:  Curr Opin Neurol        ISSN: 1350-7540            Impact factor:   5.710


  25 in total

1.  Bifocal extradural cortical stimulation-induced recovery of consciousness in the permanent post-traumatic vegetative state.

Authors:  Sergio Canavero; Barbara Massa-Micon; Franco Cauda; Elisa Montanaro
Journal:  J Neurol       Date:  2009-02-28       Impact factor: 4.849

2.  Wakefulness and loss of awareness: brain and brainstem interaction in the vegetative state.

Authors:  S Silva; X Alacoque; O Fourcade; K Samii; P Marque; R Woods; J Mazziotta; F Chollet; I Loubinoux
Journal:  Neurology       Date:  2010-01-26       Impact factor: 9.910

Review 3.  [Ethical aspects of dealing with coma patients].

Authors:  Karl Ungersböck
Journal:  Wien Med Wochenschr       Date:  2009

4.  Comparison of the Full Outline of UnResponsiveness and Glasgow Liege Scale/Glasgow Coma Scale in an intensive care unit population.

Authors:  Marie-Aurélie Bruno; Didier Ledoux; Bernard Lambermont; François Damas; Caroline Schnakers; Audrey Vanhaudenhuyse; Olivia Gosseries; Steven Laureys
Journal:  Neurocrit Care       Date:  2011-12       Impact factor: 3.210

5.  Dissociations between behavioural and functional magnetic resonance imaging-based evaluations of cognitive function after brain injury.

Authors:  Jonathan C Bardin; Joseph J Fins; Douglas I Katz; Jennifer Hersh; Linda A Heier; Karsten Tabelow; Jonathan P Dyke; Douglas J Ballon; Nicholas D Schiff; Henning U Voss
Journal:  Brain       Date:  2011-03       Impact factor: 13.501

Review 6.  From unresponsive wakefulness to minimally conscious PLUS and functional locked-in syndromes: recent advances in our understanding of disorders of consciousness.

Authors:  Marie-Aurélie Bruno; Audrey Vanhaudenhuyse; Aurore Thibaut; Gustave Moonen; Steven Laureys
Journal:  J Neurol       Date:  2011-06-16       Impact factor: 4.849

7.  On consciousness, resting state fMRI, and neurodynamics.

Authors:  Arvid Lundervold
Journal:  Nonlinear Biomed Phys       Date:  2010-06-03

8.  Vagus nerve stimulation to augment recovery from severe traumatic brain injury impeding consciousness: a prospective pilot clinical trial.

Authors:  Chen Shi; Steven R Flanagan; Uzma Samadani
Journal:  Neurol Res       Date:  2013-04       Impact factor: 2.448

9.  Learning as a possible sign of non-reflective consciousness in persons with a diagnosis of vegetative state and pervasive motor impairment.

Authors:  Andrea Bosco; Giulio E Lancioni; Marta Olivetti Belardinelli; Nirbhay N Singh; Mark F O'Reilly; Jeff Sigafoos
Journal:  Cogn Process       Date:  2009-08-20

10.  Functional neuroimaging and withdrawal of life-sustaining treatment from vegetative patients.

Authors:  D J Wilkinson; G Kahane; M Horne; J Savulescu
Journal:  J Med Ethics       Date:  2009-08       Impact factor: 2.903

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