Literature DB >> 1799084

Hepatitis B surface and e antigen seropositivity in mothers and cord blood at Port Moresby General Hospital: implications for a control program.

M Sapuri1, D M Babona, C A Klufio, J D Vince.   

Abstract

Analysis of 100 unselected paired maternal and cord blood samples showed 11 mothers to be HBsAg positive and 6 of these to be also HBeAg positive. 5 cord blood samples were HBsAg positive and 3 were HBeAg positive. Assuming a protective efficacy rate of 75%, the present plasma-derived hepatitis B virus vaccine control program is likely to prevent the perinatal acquisition of the hepatitis B virus carrier state in 27 per 1000 children. The addition of immunoglobulin prophylaxis would be likely to reduce this by another 5 per 1000, but its use does not appear practicable at the present time.

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Keywords:  Age Factors; Biology; Cost Benefit Analysis; Delivery Of Health Care; Demographic Factors; Developing Countries; Diseases; Evaluation; Health; Health Services; Hematological Effects; Hemic System; Immunity; Immunity, Active; Immunization; Immunoglobulin Alterations; Immunologic Factors; Infant; Liver Cirrhosis; Liver Dysfunction; Liver Neoplasms; Melanesia; Neoplasms; Oceania; Papua New Guinea; Physiology; Population; Population Characteristics; Primary Health Care; Quantitative Evaluation; Recommendations; Research Report; Vaccination; Viral Diseases--prevention and control; Youth

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Year:  1991        PMID: 1799084

Source DB:  PubMed          Journal:  P N G Med J        ISSN: 0031-1480


  1 in total

1.  Hepatitis B surface antigen seroprevalence among children in Papua New Guinea, 2012-2013.

Authors:  Russel Kitau; Siddhartha Sankar Datta; Minal K Patel; Karen Hennessey; Kathleen Wannemuehler; Gerard Sui; William Lagani
Journal:  Am J Trop Med Hyg       Date:  2015-01-12       Impact factor: 2.345

  1 in total

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