| Literature DB >> 17988836 |
Kevin J Balbi1, Edward J Feil.
Abstract
It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We outline an approach to explore the dynamics of this process, and highlight its profound implications.Mesh:
Year: 2007 PMID: 17988836 DOI: 10.1016/j.resmic.2007.09.005
Source DB: PubMed Journal: Res Microbiol ISSN: 0923-2508 Impact factor: 3.992