Literature DB >> 1798792

Hypoglycemic effects of sesquiterpene glycosides and polyhydroxylated triterpenoids of Eriobotrya japonica.

N De Tommasi1, F De Simone, G Cirino, C Cicala, C Pizza.   

Abstract

The effects of the constituent sesquiterpene glycosides 1-3 and polyhydroxylated triterpenoids 5-6 isolated by MeOH extraction of Eriobotrya japonica were studied in genetically diabetic mice (C57BL/KS-db/db/Ola) and normoglycemic rats. The sesquiterpene glycoside 3 and the polyhydroxylated triterpenoids 5 and 6 produced a marked inhibition of glycosuria. Furthermore, 5 and 6 were able to reduce blood glucose levels in normoglycemic rats. While there are already some data reported on hypoglycemic activity of polyhydroxylated triterpenoids, there are no previous data showing hypoglycemic activity of sesquiterpene glycosides.

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Year:  1991        PMID： 1798792     DOI： 10.1055/s-2006-960137

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  10 in total

1.  Isolation and antimicrobial and antioxidant evaluation of bio-active compounds from eriobotrya japonica stems.

Authors:  Khaled Nabih Rashed; Monica Butnariu
Journal:  Adv Pharm Bull       Date:  2013-12-23

2.  Anti-inflammatory and antioxidant properties of Eriobotrya japonica leaves extracts.

Authors:  Kammoun Maher; Ben Ali Yassine; Bezzine Sofiane
Journal:  Afr Health Sci       Date:  2015-06       Impact factor: 0.927

3.  Development of simultaneous interaction prediction approach (SiPA) for the expansion of interaction network of traditional Chinese medicine.

Authors:  Mengjie Rui; Hui Pang; Wei Ji; Siqi Wang; Xuefei Yu; Lilong Wang; Chunlai Feng
Journal:  Chin Med       Date:  2020-08-26       Impact factor: 5.455

4.  Hypoglycemic and Hepatoprotective Activity of Fermented Fruit Juice of Morinda citrifolia (Noni) in Diabetic Rats.

Authors:  B Shivananda Nayak; Julien R Marshall; Godwin Isitor; Andrew Adogwa
Journal:  Evid Based Complement Alternat Med       Date:  2010-10-14       Impact factor: 2.629

5.  A pharmacological appraisal of medicinal plants with antidiabetic potential.

Authors:  Vasim Khan; Abul Kalam Najmi; Mohd Akhtar; Mohd Aqil; Mohd Mujeeb; K K Pillai
Journal:  J Pharm Bioallied Sci       Date:  2012-01

6.  Systems pharmacology dissection of the anti-inflammatory mechanism for the medicinal herb Folium eriobotryae.

Authors:  Jingxiao Zhang; Yan Li; Su-Shing Chen; Lilei Zhang; Jinghui Wang; Yinfeng Yang; Shuwei Zhang; Yanqiu Pan; Yonghua Wang; Ling Yang
Journal:  Int J Mol Sci       Date:  2015-01-28       Impact factor: 5.923

Review 7.  Morinda citrifolia Linn. (Noni) and Its Potential in Obesity-Related Metabolic Dysfunction.

Authors:  Aline Carla Inada; Priscila Silva Figueiredo; Rosângela Aparecida Dos Santos-Eichler; Karine de Cássia Freitas; Priscila Aiko Hiane; Alinne Pereira de Castro; Rita de Cássia Avellaneda Guimarães
Journal:  Nutrients       Date:  2017-05-25       Impact factor: 5.717

8.  Total Sesquiterpene Glycosides from Loquat Leaves Ameliorate HFD-Induced Insulin Resistance by Modulating IRS-1/GLUT4, TRPV1, and SIRT6/Nrf2 Signaling Pathways.

Authors:  Ruoyun Wu; Tunyu Jian; Xiaoqin Ding; Han Lv; Xiuhua Meng; Bingru Ren; Jing Li; Jian Chen; Weilin Li
Journal:  Oxid Med Cell Longev       Date:  2021-10-27       Impact factor: 6.543

9.  Processing technology investigation of loquat (Eriobotrya japonica) leaf by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry combined with chemometrics.

Authors:  Labin Wu; Xue Jiang; Linfang Huang; Shilin Chen
Journal:  PLoS One       Date:  2013-05-07       Impact factor: 3.240

10.  INVASIVE ALIEN PLANT SPECIES USED FOR THE TREATMENT OF VARIOUS DISEASES IN LIMPOPO PROVINCE, SOUTH AFRICA.

Authors:  Lesibana Peter Maema; Martin Potgieter; Salome Mamokone Mahlo
Journal:  Afr J Tradit Complement Altern Med       Date:  2016-07-03
  10 in total

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