Literature DB >> 17987353

History and perspectives of medical research at the Albert Schweitzer Hospital in Lambaréné, Gabon.

Michael Ramharter1, Ayola A Adegnika, Selidji T Agnandji, Pierre Blaise Matsiegui, Martin P Grobusch, Stefan Winkler, Wolfgang Graninger, Sanjeev Krishna, Maria Yazdanbakhsh, Benjamin Mordmüller, Bertrand Lell, Michel A Missinou, Elie Mavoungou, Saadou Issifou, Peter G Kremsner.   

Abstract

In 1913 Albert Schweitzer founded one of the first modern hospitals in Africa dedicated to the health of the local population. The Albert Schweitzer Hospital is located in Lambaréné, a small town in Gabon. In 1981 a research department--the Medical Research Unit--was established with the aim to perform research in the field of infectious diseases ( www.lambarene.org ). The main focus lies on clinical research on malaria and other parasitic diseases. Studies on the molecular biology and immunology of parasitic diseases are fostered since the inauguration of a novel building dedicated for basic science. A training program in clinical research in tropical diseases for African scientists has been set up recently.

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Year:  2007        PMID： 17987353     DOI： 10.1007/s00508-007-0857-5

Source DB:  PubMed          Journal:  Wien Klin Wochenschr        ISSN： 0043-5325            Impact factor:   2.275


  33 in total

1.  Randomized controlled trial of fosmidomycin-clindamycin versus sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malaria.

Authors:  Sunny Oyakhirome; Saadou Issifou; Peter Pongratz; Fortune Barondi; Michael Ramharter; Jürgen F Kun; Michel A Missinou; Bertrand Lell; Peter G Kremsner
Journal:  Antimicrob Agents Chemother       Date:  2007-02-26       Impact factor: 5.191

2.  Cortisol and susceptibility to malaria during pregnancy.

Authors:  Marielle K Bouyou-Akotet; Ayola A Adegnika; Selidji T Agnandji; Edouard Ngou-Milama; Maryvonne Kombila; Peter G Kremsner; Elie Mavoungou
Journal:  Microbes Infect       Date:  2005 Aug-Sep       Impact factor: 2.700

3.  A Duffy binding-like domain is involved in the NKp30-mediated recognition of Plasmodium falciparum-parasitized erythrocytes by natural killer cells.

Authors:  Elie Mavoungou; Jana Held; Ludovic Mewono; Peter G Kremsner
Journal:  J Infect Dis       Date:  2007-04-03       Impact factor: 5.226

4.  Short-course regimens of artesunate-fosmidomycin in treatment of uncomplicated Plasmodium falciparum malaria.

Authors:  Steffen Borrmann; Ayola A Adegnika; Félicien Moussavou; Sunny Oyakhirome; Gilbert Esser; Pierre-Blaise Matsiegui; Michael Ramharter; Ingrid Lundgren; Maryvonne Kombila; Saadou Issifou; David Hutchinson; Jochen Wiesner; Hassan Jomaa; Peter G Kremsner
Journal:  Antimicrob Agents Chemother       Date:  2005-09       Impact factor: 5.191

5.  Randomised placebo-controlled study of atovaquone plus proguanil for malaria prophylaxis in children.

Authors:  B Lell; D Luckner; M Ndjavé; T Scott; P G Kremsner
Journal:  Lancet       Date:  1998-03-07       Impact factor: 79.321

Review 6.  Allergy, parasites, and the hygiene hypothesis.

Authors:  Maria Yazdanbakhsh; Peter G Kremsner; Ronald van Ree
Journal:  Science       Date:  2002-04-19       Impact factor: 47.728

7.  Interferon-gamma responses are associated with resistance to reinfection with Plasmodium falciparum in young African children.

Authors:  A J Luty; B Lell; R Schmidt-Ott; L G Lehman; D Luckner; B Greve; P Matousek; K Herbich; D Schmid; F Migot-Nabias; P Deloron; R S Nussenzweig; P G Kremsner
Journal:  J Infect Dis       Date:  1999-04       Impact factor: 5.226

8.  Shared breastfeeding in central Africa.

Authors:  Michael Ramharter; Sanders K Chai; Ayola A Adegnika; Anna Klöpfer; Matthias Längin; Selidji T Agnandji; Sunny Oyakhirome; Norbert G Schwarz; Martin P Grobusch; Saadon Issifou; Peter G Kremsner
Journal:  AIDS       Date:  2004-09-03       Impact factor: 4.177

9.  Curing of chloroquine-resistant malaria with clindamycin.

Authors:  P G Kremsner; S Winkler; C Brandts; W Graninger; U Bienzle
Journal:  Am J Trop Med Hyg       Date:  1993-11       Impact factor: 2.345

10.  Comparison of chlorproguanil-dapsone with sulfadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in young African children: double-blind randomised controlled trial.

Authors:  A Alloueche; W Bailey; S Barton; J Bwika; P Chimpeni; C O Falade; F A Fehintola; J Horton; S Jaffar; T Kanyok; P G Kremsner; J G Kublin; T Lang; M A Missinou; C Mkandala; A M J Oduola; Z Premji; L Robertson; A Sowunmi; S A Ward; P A Winstanley
Journal:  Lancet       Date:  2004-06-05       Impact factor: 79.321
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  34 in total

1.  Medical research at the Albert Schweitzer Hospital.

Authors:  Saadou Issifou; Ayola A Adegnika; Bertrand Lell
Journal:  Wien Klin Wochenschr       Date:  2010-03       Impact factor: 1.704

2.  Tropical medicine at the University of Tübingen.

Authors:  Peter Gottfried Kremsner
Journal:  Wien Klin Wochenschr       Date:  2010-03       Impact factor: 1.704

3.  Prospective Clinical Trial Assessing Species-Specific Efficacy of Artemether-Lumefantrine for the Treatment of Plasmodium malariae, Plasmodium ovale, and Mixed Plasmodium Malaria in Gabon.

Authors:  Mirjam Groger; Luzia Veletzky; Albert Lalremruata; Chiara Cattaneo; Johannes Mischlinger; Rella Zoleko-Manego; Lilian Endamne; Anna Klicpera; Johanna Kim; The Nguyen; Lena Flohr; Jonathan Remppis; Pierre-Blaise Matsiegui; Ayôla A Adegnika; Selidji T Agnandji; Peter G Kremsner; Benjamin Mordmüller; Ghyslain Mombo-Ngoma; Michael Ramharter
Journal:  Antimicrob Agents Chemother       Date:  2018-02-23       Impact factor: 5.191

4.  Parasites and pregnancy.

Authors:  Meral Esen; Benjamin Mordmüller
Journal:  Wien Klin Wochenschr       Date:  2007       Impact factor: 1.704

5.  Tuberculosis Treatment Outcome and Drug Resistance in Lambaréné, Gabon: A Prospective Cohort Study.

Authors:  Sabine Bélard; Jonathan Remppis; Sanne Bootsma; Saskia Janssen; Davy U Kombila; Justin O Beyeme; Elie G Rossatanga; Cosme Kokou; Kara K Osbak; Régis M Obiang Mba; Harry M Kaba; Afsatou N Traoré; Jonas Ehrhardt; Emmanuel B Bache; Arnaud Flamen; Sabine Rüsch-Gerdes; Matthias Frank; Ayôla A Adegnika; Bertrand Lell; Stefan Niemann; Peter G Kremsner; Marguerite M Loembé; Abraham S Alabi; Martin P Grobusch
Journal:  Am J Trop Med Hyg       Date:  2016-06-27       Impact factor: 2.345

6.  In vitro activity of antifungal drugs against Plasmodium falciparum field isolates.

Authors:  Peter Pongratz; Florian Kurth; Ghyslain Mombo Ngoma; Arti Basra; Michael Ramharter
Journal:  Wien Klin Wochenschr       Date:  2011-07-07       Impact factor: 1.704

7.  Pharmacokinetics of ferroquine, a novel 4-aminoquinoline, in asymptomatic carriers of Plasmodium falciparum infections.

Authors:  Christian Supan; Ghyslain Mombo-Ngoma; Matthias P Dal-Bianco; Carmen L Ospina Salazar; Saadou Issifou; Florent Mazuir; Aziz Filali-Ansary; Christophe Biot; Daniel Ter-Minassian; Michael Ramharter; Peter G Kremsner; Bertrand Lell
Journal:  Antimicrob Agents Chemother       Date:  2012-03-19       Impact factor: 5.191

8.  Randomized, controlled, assessor-blind clinical trial to assess the efficacy of single- versus repeated-dose albendazole to treat ascaris lumbricoides, trichuris trichiura, and hookworm infection.

Authors:  Ayola A Adegnika; Jeannot F Zinsou; Saadou Issifou; Ulysse Ateba-Ngoa; Roland F Kassa; Eliane N Feugap; Yabo J Honkpehedji; Jean-Claude Dejon Agobe; Hilaire M Kenguele; Marguerite Massinga-Loembe; Selidji T Agnandji; Benjamin Mordmüller; Michael Ramharter; Maria Yazdanbakhsh; Peter G Kremsner; Bertrand Lell
Journal:  Antimicrob Agents Chemother       Date:  2014-02-18       Impact factor: 5.191

9.  Population Pharmacokinetics of Mefloquine Intermittent Preventive Treatment for Malaria in Pregnancy in Gabon.

Authors:  Michael Ramharter; Matthias Schwab; Clara Menendez; Reinhold Kerb; Thorsten Lehr; Ghyslain Mombo-Ngoma; Rella Zoleko Manego; Daisy Akerey-Diop; Arti Basra; Jean-Rodolphe Mackanga; Heike Würbel; Jan-Georg Wojtyniak; Raquel Gonzalez; Ute Hofmann; Mirjam Geditz; Pierre-Blaise Matsiegui; Peter G Kremsner
Journal:  Antimicrob Agents Chemother       Date:  2019-01-29       Impact factor: 5.191

10.  Increased prevalence of intestinal helminth infection during pregnancy in a Sub-Saharan African community.

Authors:  Ayola A Adegnika; Selidji T Agnandji; Sanders K Chai; Michael Ramharter; Lutz Breitling; Eric Kendjo; Saadou Issifou; Maria Yazdanbakhsh; Maryvonne Kombila; Peter G Kremsner
Journal:  Wien Klin Wochenschr       Date:  2007       Impact factor: 1.704
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