Literature DB >> 17986100

Long-term effect of intravenous immunoglobulin on anti-MuSK antibody-positive myasthenia gravis.

A Shibata-Hamaguchi1, M Samuraki, E Furui, K Iwasa, H Yoshikawa, S Hayashi, M Yamada.   

Abstract

Anti-muscle-specific receptor tyrosine kinase (MuSK) antibody-positive myasthenia gravis (MG) patients show various responses to conventional immunosuppressive treatment and some patients are resistant to these therapies. We report a 50-year-old Japanese man with anti-MuSK antibody-positive MG, who showed no or poor response to various therapies, including plasmapheresis, corticosteroid, and tacrolimus. The patient was then treated with intravenous immunoglobulin (IVIG), and showed a good response that persisted over 20 months. The outcome of this case suggests that IVIG treatment may be an effective therapeutic option for anti-MuSK antibody-positive MG, with a potentially long-term effect.

Entities:  

Mesh:

Substances:

Year:  2007        PMID: 17986100     DOI: 10.1111/j.1600-0404.2007.00877.x

Source DB:  PubMed          Journal:  Acta Neurol Scand        ISSN: 0001-6314            Impact factor:   3.209


  4 in total

Review 1.  [Administration of intravenous immunoglobulins in neurology. An evidence-based consensus: update 2010].

Authors:  M Stangel; R Gold
Journal:  Nervenarzt       Date:  2011-04       Impact factor: 1.214

Review 2.  Muscle-Specific Tyrosine Kinase and Myasthenia Gravis Owing to Other Antibodies.

Authors:  Michael H Rivner; Mamatha Pasnoor; Mazen M Dimachkie; Richard J Barohn; Lin Mei
Journal:  Neurol Clin       Date:  2018-05       Impact factor: 3.806

3.  Anti-MuSK Antibody-positive Myasthenia Gravis Successfully Treated with Outpatient Periodic Weekly Blood Purification Therapy.

Authors:  Kentaro Deguchi; Kosuke Matsuzono; Yumiko Nakano; Syoichiro Kono; Kota Sato; Shoko Deguchi; Katsuyuki Tanabe; Nozomi Hishikawa; Yasuyuki Ota; Toru Yamashita; Kiyoe Ohta; Masakatsu Motomura; Koji Abe
Journal:  Intern Med       Date:  2018-01-11       Impact factor: 1.271

Review 4.  Muscle-Specific Kinase Myasthenia Gravis.

Authors:  Lucia S Borges; David P Richman
Journal:  Front Immunol       Date:  2020-05-08       Impact factor: 7.561

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.