Literature DB >> 17984233

Intranasal granulocyte-macrophage colony-stimulating factor reduces the Aspergillus burden in an immunosuppressed murine model of pulmonary aspergillosis.

Gerardo Quezada1, Nadezhda V Koshkina, Patrick Zweidler-McKay, Zichao Zhou, Dimitrios P Kontoyiannis, Eugenie S Kleinerman.   

Abstract

We demonstrated that intranasal granulocyte-macrophage colony-stimulating factor given to immunosuppressed mice infected with pulmonary aspergillosis resulted in a sixfold reduction in the lung fungal burden compared to the result for saline-treated mice (P = 0.045). These data suggest that lung-targeted immunotherapy may be complementary to antifungal agents and may improve patient responses.

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Year:  2007        PMID： 17984233      PMCID： PMC2224773          DOI： 10.1128/AAC.00760-07

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  19 in total

Review 1.  Invasive aspergillosis in 2002: an update.

Authors:  D P Kontoyiannis; G P Bodey
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2002-03-22       Impact factor: 3.267

Review 2.  Antigen markers of macrophage differentiation in murine tissues.

Authors:  S Gordon; L Lawson; S Rabinowitz; P R Crocker; L Morris; V H Perry
Journal:  Curr Top Microbiol Immunol       Date:  1992       Impact factor: 4.291

3.  F4/80, a monoclonal antibody directed specifically against the mouse macrophage.

Authors:  J M Austyn; S Gordon
Journal:  Eur J Immunol       Date:  1981-10       Impact factor: 5.532

4.  Comparative analysis of amphotericin B lipid complex and liposomal amphotericin B kinetics of lung accumulation and fungal clearance in a murine model of acute invasive pulmonary aspergillosis.

Authors:  Russell E Lewis; Guangling Liao; Jinggou Hou; Georgios Chamilos; Randall A Prince; Dimitrios P Kontoyiannis
Journal:  Antimicrob Agents Chemother       Date:  2007-01-29       Impact factor: 5.191

5.  Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate.

Authors:  J C Bowman; G K Abruzzo; J W Anderson; A M Flattery; C J Gill; V B Pikounis; D M Schmatz; P A Liberator; C M Douglas
Journal:  Antimicrob Agents Chemother       Date:  2001-12       Impact factor: 5.191

6.  Itraconazole preexposure attenuates the efficacy of subsequent amphotericin B therapy in a murine model of acute invasive pulmonary aspergillosis.

Authors:  Russell E Lewis; Randall A Prince; Jingduan Chi; Dimitrios P Kontoyiannis
Journal:  Antimicrob Agents Chemother       Date:  2002-10       Impact factor: 5.191

7.  Pharmacodynamics of caspofungin in a murine model of invasive pulmonary aspergillosis: evidence of concentration-dependent activity.

Authors:  Nathan P Wiederhold; Dimitrios P Kontoyiannis; Jingduan Chi; Randall A Prince; Vincent H Tam; Russell E Lewis
Journal:  J Infect Dis       Date:  2004-09-10       Impact factor: 5.226

8.  Polyene and cytokine treatment of experimental aspergillosis.

Authors:  Edward Sionov; Esther Segal
Journal:  FEMS Immunol Med Microbiol       Date:  2003-12-05

9.  Aerosolized granulocyte macrophage colony-stimulating factor (GM-CSF) therapy in metastatic cancer.

Authors:  Ravi D Rao; Peter M Anderson; Carola A S Arndt; Peter J Wettstein; Svetomir N Markovic
Journal:  Am J Clin Oncol       Date:  2003-10       Impact factor: 2.339

10.  Mononuclear phagocyte system of the mouse defined by immunohistochemical localization of antigen F4/80. Identification of resident macrophages in renal medullary and cortical interstitium and the juxtaglomerular complex.

Authors:  D A Hume; S Gordon
Journal:  J Exp Med       Date:  1983-05-01       Impact factor: 14.307
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  10 in total

1.  Cytokine gene polymorphisms and the outcome of invasive candidiasis: a prospective cohort study.

Authors:  Melissa D Johnson; Theo S Plantinga; Esther van de Vosse; Digna R Velez Edwards; P Brian Smith; Barbara D Alexander; John C Yang; Dennis Kremer; Gregory M Laird; Marije Oosting; Leo A B Joosten; Jos W M van der Meer; Jaap T van Dissel; Thomas J Walsh; John R Perfect; Bart-Jan Kullberg; William K Scott; Mihai G Netea
Journal:  Clin Infect Dis       Date:  2011-12-05       Impact factor: 9.079

2.  Role of Granulocyte-Macrophage Colony-Stimulating Factor Signaling in Regulating Neutrophil Antifungal Activity and the Oxidative Burst During Respiratory Fungal Challenge.

Authors:  Shinji Kasahara; Anupam Jhingran; Sourabh Dhingra; Anand Salem; Robert A Cramer; Tobias M Hohl
Journal:  J Infect Dis       Date:  2016-02-09       Impact factor: 5.226

Review 3.  Immune responses to invasive aspergillosis: new understanding and therapeutic opportunities.

Authors:  Tobias M Hohl
Journal:  Curr Opin Infect Dis       Date:  2017-08       Impact factor: 4.915

4.  Granulocyte macrophage colony-stimulating factor in 66 patients with myeloid or lymphoid neoplasms and recipients of hematopoietic stem cell transplantation with invasive fungal disease.

Authors:  Amar Safdar; Gilhen Rodriguez; Jorge Zuniga; Fadi Al Akhrass; Georgia Georgescu; Anupam Pande
Journal:  Acta Haematol       Date:  2012-10-02       Impact factor: 2.195

5.  Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy.

Authors:  I D Jacobsen; S Brunke; K Seider; T Schwarzmüller; A Firon; C d'Enfért; K Kuchler; B Hube
Journal:  Infect Immun       Date:  2009-12-14       Impact factor: 3.441

6.  Immunotherapeutic effects of recombinant adenovirus encoding granulocyte-macrophage colony-stimulating factor in experimental pulmonary tuberculosis.

Authors:  A Francisco-Cruz; D Mata-Espinosa; S Estrada-Parra; Z Xing; R Hernández-Pando
Journal:  Clin Exp Immunol       Date:  2013-03       Impact factor: 4.330

7.  Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America.

Authors:  Thomas F Patterson; George R Thompson; David W Denning; Jay A Fishman; Susan Hadley; Raoul Herbrecht; Dimitrios P Kontoyiannis; Kieren A Marr; Vicki A Morrison; M Hong Nguyen; Brahm H Segal; William J Steinbach; David A Stevens; Thomas J Walsh; John R Wingard; Jo-Anne H Young; John E Bennett
Journal:  Clin Infect Dis       Date:  2016-06-29       Impact factor: 9.079

8.  Collaboration between macrophages and vaccine-induced CD4+ T cells confers protection against lethal Pseudomonas aeruginosa pneumonia during neutropenia.

Authors:  Akinobu Kamei; Weihui Wu; David C Traficante; Andrew Y Koh; Nico Van Rooijen; Gerald B Pier; Gregory P Priebe
Journal:  J Infect Dis       Date:  2012-10-24       Impact factor: 5.226

Review 9.  Modulating host immune responses to fight invasive fungal infections.

Authors:  James E Scriven; Mark W Tenforde; Stuart M Levitz; Joseph N Jarvis
Journal:  Curr Opin Microbiol       Date:  2017-11-15       Impact factor: 7.934

Review 10.  Respiratory tract infections and pneumonia.

Authors:  Susan McChlery; Gordon Ramage; Jeremy Bagg
Journal:  Periodontol 2000       Date:  2009-02       Impact factor: 7.589
  10 in total

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