| Literature DB >> 17983577 |
Tomohiro Tanaka1, Yo-Ichi Nabeshima.
Abstract
NAD plays an essential role in a number of biological processes. A study in this issue of Cell Metabolism (Revollo et al., 2007b) demonstrates that nicotinamide phosphoribosyltransferase (Nampt), also known as PBEF or visfatin, is a secreted enzyme and a source of systemic NAD. The authors show that Nampt-mediated NAD synthesis is necessary for beta cell function, providing fresh insights into the pathophysiology of metabolic diseases.Entities:
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Year: 2007 PMID： 17983577 DOI： 10.1016/j.cmet.2007.10.004
Source DB: PubMed Journal: Cell Metab ISSN： 1550-4131 Impact factor: 27.287