Literature DB >> 17983570

Wnt signaling: it gets more humorous with age.

Bryan D White1, Nghi K Nguyen, Randall T Moon.   

Abstract

In addition to its myriad of contributions in development, disease and regeneration, recent research implicates the Wnt/beta-catenin signaling cascade in yet another biological process - aging. The latest role of Wnt uncovers new complexities and opportunities for modulating the Wnt/beta-catenin pathway in regenerative medicine.

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Year:  2007        PMID： 17983570     DOI： 10.1016/j.cub.2007.08.062

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  19 in total

1.  Complement C1q activates canonical Wnt signaling and promotes aging-related phenotypes.

Authors:  Atsuhiko T Naito; Tomokazu Sumida; Seitaro Nomura; Mei-Lan Liu; Tomoaki Higo; Akito Nakagawa; Katsuki Okada; Taku Sakai; Akihito Hashimoto; Yurina Hara; Ippei Shimizu; Weidong Zhu; Haruhiro Toko; Akemi Katada; Hiroshi Akazawa; Toru Oka; Jong-Kook Lee; Tohru Minamino; Toshio Nagai; Kenneth Walsh; Akira Kikuchi; Misako Matsumoto; Marina Botto; Ichiro Shiojima; Issei Komuro
Journal:  Cell       Date:  2012-06-08       Impact factor: 41.582

2.  Targeted inhibition of β-catenin/CBP signaling ameliorates renal interstitial fibrosis.

Authors:  Sha Hao; Weichun He; Yingjian Li; Hong Ding; Yayi Hou; Jing Nie; Fan Fan Hou; Michael Kahn; Youhua Liu
Journal:  J Am Soc Nephrol       Date:  2011-08-04       Impact factor: 10.121

3.  Negative feedback regulation of Wnt signaling by Gbetagamma-mediated reduction of Dishevelled.

Authors:  Hwajin Jung; Hyun Joon Kim; Suk Kyung Lee; Rokki Kim; Will Kopachik; Jin-Kwan Han; Eek-hoon Jho
Journal:  Exp Mol Med       Date:  2009-10-31       Impact factor: 8.718

4.  Inhibition of Wnt/β-catenin signal is alleviated reactive gliosis in rats with hydrocephalus.

Authors:  Hao Xu; Bin Xu; ZhanXiang Wang; GuoWei Tan; ShangHang Shen
Journal:  Childs Nerv Syst       Date:  2015-01-07       Impact factor: 1.475

Review 5.  Bone marrow mesenchymal stem cells: Aging and tissue engineering applications to enhance bone healing.

Authors:  Hang Lin; Jihee Sohn; He Shen; Mark T Langhans; Rocky S Tuan
Journal:  Biomaterials       Date:  2018-06-22       Impact factor: 12.479

6.  Plasminogen activator inhibitor-1 is a transcriptional target of the canonical pathway of Wnt/beta-catenin signaling.

Authors:  Weichun He; Ruoyun Tan; Chunsun Dai; Yingjian Li; Dan Wang; Sha Hao; Michael Kahn; Youhua Liu
Journal:  J Biol Chem       Date:  2010-06-02       Impact factor: 5.157

7.  Wnt/beta-catenin signaling promotes renal interstitial fibrosis.

Authors:  Weichun He; Chunsun Dai; Yingjian Li; Gang Zeng; Satdarshan P Monga; Youhua Liu
Journal:  J Am Soc Nephrol       Date:  2009-03-18       Impact factor: 10.121

Review 8.  New insights into epithelial-mesenchymal transition in kidney fibrosis.

Authors:  Youhua Liu
Journal:  J Am Soc Nephrol       Date:  2009-12-17       Impact factor: 10.121

9.  Multiple genes of the renin-angiotensin system are novel targets of Wnt/β-catenin signaling.

Authors:  Lili Zhou; Yingjian Li; Sha Hao; Dong Zhou; Roderick J Tan; Jing Nie; Fan Fan Hou; Michael Kahn; Youhua Liu
Journal:  J Am Soc Nephrol       Date:  2014-07-10       Impact factor: 10.121

Review 10.  Epithelial phenotype and the RPE: is the answer blowing in the Wnt?

Authors:  Janice M Burke
Journal:  Prog Retin Eye Res       Date:  2008-08-19       Impact factor: 21.198
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