OBJECTIVE: To determine the short- and long-term effects of an intensive, concentrated rehabilitation programme in patients with chronic heart failure. DESIGN: Randomized controlled trial, with one-month and six-year evaluations. SETTING:Residential rehabilitation centre in Switzerland. SUBJECTS:Fifty patients with chronic heart failure, randomized to exercise or control groups. INTERVENTIONS: A rehabilitation programme lasting one month, including educational sessions, a low-fat diet, and 2 hours of individually prescribed exercise daily. MAIN MEASURES: Exercise test responses, health outcomes and physical activity patterns. RESULTS:Peak Vo(2) increased 21.4% in the exercise group during the rehabilitation programme (P<0.05), whereas peak Vo(2) did not change among controls. After the six-year follow-up period, peak Vo(2) was only slightly higher than that at baseline in the trained group (7%, NS), while peak Vo(2) among controls was unchanged. During long-term follow-up, 9 and 12 patients died in the exercise and control groups, respectively (P = 0.63). At six years, physical activity patterns tended to be higher in the exercise group; the mean energy expenditure values over the last year were 2,704 +/- 1,970 and 2,085 +/- 1,522 kcal/week during recreational activities for the exercise and control groups, respectively. However, both groups were more active compared to energy expenditure prior to their cardiac event (P<0.001). CONCLUSIONS: Six years after participation in a residential rehabilitation programme, patients with chronic heart failure had slightly better outcomes than control subjects, maintained exercise capacity and engaged in activities that exceed the minimal amount recommended by guidelines for cardiovascular health.
RCT Entities:
OBJECTIVE: To determine the short- and long-term effects of an intensive, concentrated rehabilitation programme in patients with chronic heart failure. DESIGN: Randomized controlled trial, with one-month and six-year evaluations. SETTING: Residential rehabilitation centre in Switzerland. SUBJECTS: Fifty patients with chronic heart failure, randomized to exercise or control groups. INTERVENTIONS: A rehabilitation programme lasting one month, including educational sessions, a low-fat diet, and 2 hours of individually prescribed exercise daily. MAIN MEASURES: Exercise test responses, health outcomes and physical activity patterns. RESULTS: Peak Vo(2) increased 21.4% in the exercise group during the rehabilitation programme (P<0.05), whereas peak Vo(2) did not change among controls. After the six-year follow-up period, peak Vo(2) was only slightly higher than that at baseline in the trained group (7%, NS), while peak Vo(2) among controls was unchanged. During long-term follow-up, 9 and 12 patients died in the exercise and control groups, respectively (P = 0.63). At six years, physical activity patterns tended to be higher in the exercise group; the mean energy expenditure values over the last year were 2,704 +/- 1,970 and 2,085 +/- 1,522 kcal/week during recreational activities for the exercise and control groups, respectively. However, both groups were more active compared to energy expenditure prior to their cardiac event (P<0.001). CONCLUSIONS: Six years after participation in a residential rehabilitation programme, patients with chronic heart failure had slightly better outcomes than control subjects, maintained exercise capacity and engaged in activities that exceed the minimal amount recommended by guidelines for cardiovascular health.
Authors: Rod S Taylor; Sarah Walker; Neil A Smart; Massimo F Piepoli; Fiona C Warren; Oriana Ciani; David Whellan; Christopher O'Connor; Steven J Keteyian; Andrew Coats; Constantinos H Davos; Hasnain M Dalal; Kathleen Dracup; Lorraine S Evangelista; Kate Jolly; Jonathan Myers; Birgitta B Nilsson; Claudio Passino; Miles D Witham; Gloria Y Yeh Journal: J Am Coll Cardiol Date: 2019-04-02 Impact factor: 24.094
Authors: Rod S Taylor; Sarah Walker; Neil A Smart; Massimo F Piepoli; Fiona C Warren; Oriana Ciani; Christopher O'Connor; David Whellan; Steven J Keteyian; Andrew Coats; Constantinos H Davos; Hasnain M Dalal; Kathleen Dracup; Lorraine Evangelista; Kate Jolly; Jonathan Myers; Robert S McKelvie; Birgitta B Nilsson; Claudio Passino; Miles D Witham; Gloria Y Yeh; Ann-Dorthe O Zwisler Journal: Eur J Heart Fail Date: 2018-09-26 Impact factor: 15.534
Authors: Francisco V Santos; Gaspar R Chiappa; Sergio Henrique Rodolpho Ramalho; Alexandra Correa Gervazoni Balbuena de Lima; Fausto Stauffer Junqueira de Souza; Lawrence P Cahalin; João Luiz Quagliotti Durigan; Isac de Castro; Gerson Cipriano Journal: Heart Fail Rev Date: 2018-01 Impact factor: 4.214
Authors: Edward J Davies; Tiffany Moxham; Karen Rees; Sally Singh; Andrew J S Coats; Shah Ebrahim; Fiona Lough; Rod S Taylor Journal: Eur J Heart Fail Date: 2010-05-21 Impact factor: 15.534
Authors: Linda Long; Ify R Mordi; Charlene Bridges; Viral A Sagar; Edward J Davies; Andrew Js Coats; Hasnain Dalal; Karen Rees; Sally J Singh; Rod S Taylor Journal: Cochrane Database Syst Rev Date: 2019-01-29
Authors: Birna Bjarnason-Wehrens; R Nebel; K Jensen; M Hackbusch; M Grilli; S Gielen; B Schwaab; B Rauch Journal: Eur J Prev Cardiol Date: 2019-06-08 Impact factor: 7.804
Authors: Rod S Taylor; Viral A Sagar; Ed J Davies; Simon Briscoe; Andrew J S Coats; Hayes Dalal; Fiona Lough; Karen Rees; Sally Singh Journal: Cochrane Database Syst Rev Date: 2014-04-27
Authors: Viral A Sagar; Edward J Davies; Simon Briscoe; Andrew J S Coats; Hasnain M Dalal; Fiona Lough; Karen Rees; Sally Singh; Rod S Taylor Journal: Open Heart Date: 2015-01-28