Literature DB >> 17981729

Role of caspase-independent apoptosis in cardiovascular diseases.

Soochan Bae1, Bhargavi Yalamarti, Peter M Kang.   

Abstract

Apoptosis plays an important role in various cardiovascular diseases, and inhibition of cardiac apoptosis shows promise as a therapeutic strategy. Caspase, a critical enzyme in the induction and execution of apoptosis, has been targeted to inhibit apoptosis. However a newly recognized caspase-independent apoptosis pathway may also play an important role in cardiac apoptosis. Yet the mechanism and the potential significance of caspase-independent apoptosis in the heart remain poorly understood. In this paper, we reviewed the literatures on the mechanism of caspase-independent apoptosis and its significance in cardiovascular diseases.

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Year:  2008        PMID： 17981729     DOI： 10.2741/2861

Source DB:  PubMed          Journal:  Front Biosci        ISSN： 1093-4715


  9 in total

1.  Linkage of cardiac gene expression profiles and ETS2 with lifespan variability in rats.

Authors:  Anna Sheydina; Maria Volkova; Liqun Jiang; Ondrej Juhasz; Jing Zhang; Hyun-Jin Tae; Maria G Perino; Mingyi Wang; Yi Zhu; Edward G Lakatta; Kenneth R Boheler
Journal:  Aging Cell       Date:  2012-02-15       Impact factor: 9.304

2.  Delayed activation of caspase-independent apoptosis during heart failure in transgenic mice overexpressing caspase inhibitor CrmA.

Authors:  Soochan Bae; Parco M Siu; Sangita Choudhury; Qingen Ke; Jun H Choi; Young Y Koh; Peter M Kang
Journal:  Am J Physiol Heart Circ Physiol       Date:  2010-09-10       Impact factor: 4.733

Review 3.  Molecular mechanisms of cardiomyocyte aging.

Authors:  Anna Sheydina; Daniel R Riordon; Kenneth R Boheler
Journal:  Clin Sci (Lond)       Date:  2011-10       Impact factor: 6.124

4.  Mitochondria to nucleus translocation of AIF in mice lacking Hsp70 during ischemia/reperfusion.

Authors:  Sangita Choudhury; Soochan Bae; Qingen Ke; Ji Yoo Lee; Jacob Kim; Peter M Kang
Journal:  Basic Res Cardiol       Date:  2011-03-09       Impact factor: 17.165

5.  Homocysteine induces cardiomyocyte dysfunction and apoptosis through p38 MAPK-mediated increase in oxidant stress.

Authors:  Xu Wang; Lei Cui; Jacob Joseph; Bingbing Jiang; David Pimental; Diane E Handy; Ronglih Liao; Joseph Loscalzo
Journal:  J Mol Cell Cardiol       Date:  2011-12-29       Impact factor: 5.000

6.  High dietary taurine inhibits myocardial apoptosis during an atherogenic diet: association with increased myocardial HSP70 and HSF-1 but not caspase 3.

Authors:  M Setyarani; A Zinellu; C Carru; A Zulli
Journal:  Eur J Nutr       Date:  2013-10-22       Impact factor: 5.614

7.  Apoptosis in cardiovascular diseases: mechanism and clinical implications.

Authors:  Nam-Ho Kim; Peter M Kang
Journal:  Korean Circ J       Date:  2010-07-26       Impact factor: 3.243

8.  Moderate and high amounts of tamoxifen in αMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death.

Authors:  Kevin Bersell; Sangita Choudhury; Mariya Mollova; Brian D Polizzotti; Balakrishnan Ganapathy; Stuart Walsh; Brian Wadugu; Shima Arab; Bernhard Kühn
Journal:  Dis Model Mech       Date:  2013-08-07       Impact factor: 5.758

9.  Renal sympathetic denervation improves myocardial apoptosis in rats with isoproterenol-induced heart failure by downregulation of tumor necrosis factor-α and nuclear factor-κB.

Authors:  Wei Yao; Neng Wang; Jin Qian; Lu Bai; Xiaoxin Zheng; Guo Hou; Xuan Qiu; Bo Yang
Journal:  Exp Ther Med       Date:  2017-08-30       Impact factor: 2.447
  9 in total

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