| Literature DB >> 17979279 |
Sylvain Favre1, Sandrine Gerber-Lemaire, Pierre Vogel.
Abstract
A sequence of highly diastereoselective functionalizations allowed transformation of a meso-methylenebis(cyclohept-3-ene-1,6-diyl diester) into an advanced precursor of the AB spiroketal of spongistatins. This route illustrates the potential of this bis-cycloheptene derivative for the synthesis of a key fragment of complex bioactive natural compounds.Entities:
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Year: 2007 PMID： 17979279 DOI： 10.1021/ol702326x
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005