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Literature DB >> 17978760

Electrochemical behavior and antioxidant and prooxidant activity of natural phenolics.

Aleksandra Simić¹, Dragan Manojlović, Dejan Segan, Marija Todorović.

Abstract

We have investigated the electrochemical oxidation of a number natural phenolics (salicylic acid, m-hydroxybenzoic acid, p-hydroxybenzoic acid, protocatechuic acid, o-coumaric acid, m-coumaric acid, p-coumaric acid, caffeic acid, quercetin and rutin) using cyclic voltammetry. The antioxidant properties of these compounds were also studied. A structural analysis of the tested phenolics suggests that multiple OH substitution and conjugation are important determinants of the free radical scavenging activity and electrochemical behavior. Compounds with low oxidation potentials (Epa lower than 0.45) showed antioxidant activity, whereas compounds with high Epa values (>0.45) act as prooxidants.

Entities: Chemical

Mesh：

Substances：

Year: 2007 PMID： 17978760 PMCID： PMC6149165 DOI： 10.3390/12102327

Source DB: PubMed Journal: Molecules ISSN： 1420-3049 Impact factor: 4.411

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