Literature DB >> 1797824

Measurement of quinine in filter paper-absorbed blood by high-performance liquid chromatography.

E K Mberu1, S A Ward, P A Winstanley, W M Watkins.   

Abstract

An adaptation of an existing high-performance liquid chromatographic assay is described for the measurement of quinine, within the therapeutic concentration range, in whole blood. This method, in particular the use of small blood samples which have been dried onto filter paper strips, has advantages for clinical and pharmacokinetic studies in the tropics on children with malaria.

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Year:  1991        PMID: 1797824     DOI: 10.1016/0378-4347(91)80213-v

Source DB:  PubMed          Journal:  J Chromatogr


  3 in total

Review 1.  Pharmacology and parasitology: integrating experimental methods and approaches to falciparum malaria.

Authors:  P A Winstanley; W M Watkins
Journal:  Br J Clin Pharmacol       Date:  1992-06       Impact factor: 4.335

Review 2.  Pharmacokinetics of quinine, chloroquine and amodiaquine. Clinical implications.

Authors:  S Krishna; N J White
Journal:  Clin Pharmacokinet       Date:  1996-04       Impact factor: 6.447

3.  Halofantrine pharmacokinetics in Kenyan children with non-severe and severe malaria.

Authors:  W M Watkins; P A Winstanley; E K Mberu; G Kokwaro; S A Murphy; C J Newton; I Mwangi; D Forster; K Marsh
Journal:  Br J Clin Pharmacol       Date:  1995-03       Impact factor: 4.335

  3 in total

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