Literature DB >> 17977741

Role of insulin-like growth factor-1R system in colorectal carcinogenesis.

Erin A Donovan1, Shivaani Kummar.   

Abstract

The insulin-like growth factor (IGF) system is comprised of receptors, ligands (IGF-I and IGF-II), and a family of binding proteins (IGFBPs). It plays an important role in growth and development and in the maintenance of normal homeostasis. We present a review of the current laboratory and epidemiologic evidence that suggests an important role of the IGF system in colorectal carcinogenesis. Due to the complexity of this system, we have focused the review on the role of the IGF-1 receptor and its ligands in colorectal carcinogenesis and the strategies to block this pathway as a potential anti-cancer therapy.

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Year:  2007        PMID： 17977741      PMCID： PMC2374741          DOI： 10.1016/j.critrevonc.2007.09.003

Source DB:  PubMed          Journal:  Crit Rev Oncol Hematol        ISSN： 1040-8428            Impact factor:   6.312


  51 in total

1.  Overexpression of the insulin-like growth factor I receptor in human colon carcinomas.

Authors:  Matthias M Weber; Christian Fottner; Sun Bin Liu; M Christina Jung; Dieter Engelhardt; Gustavo B Baretton
Journal:  Cancer       Date:  2002-11-15       Impact factor: 6.860

2.  Plasma insulin-like growth factor 1, insulin-like growth factor binding protein 3, and risk of colorectal cancer: a prospective study in northern Sweden.

Authors:  R Palmqvist; G Hallmans; S Rinaldi; C Biessy; R Stenling; E Riboli; R Kaaks
Journal:  Gut       Date:  2002-05       Impact factor: 23.059

3.  Circulating insulin-like growth factor-I levels regulate colon cancer growth and metastasis.

Authors:  Yiping Wu; Shoshana Yakar; Ling Zhao; Lothar Hennighausen; Derek LeRoith
Journal:  Cancer Res       Date:  2002-02-15       Impact factor: 12.701

4.  Insulin-like growth factor II and colorectal cancer risk in women.

Authors:  Kelly J Hunt; Paolo Toniolo; Arslan Akhmedkhanov; Annekatrin Lukanova; Henri Dechaud; Sabina Rinaldi; Anne Zeleniuch-Jacquotte; Roy E Shore; Elio Riboli; Rudolf Kaaks
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2002-09       Impact factor: 4.254

5.  Serum insulin-like growth factor I and subsequent risk of colorectal cancer among Japanese-American men.

Authors:  Abraham M Y Nomura; Grant N Stemmermann; James Lee; Michael N Pollak
Journal:  Am J Epidemiol       Date:  2003-09-01       Impact factor: 4.897

6.  Acromegaly and cancer risk: a cohort study in Sweden and Denmark.

Authors:  D Baris; G Gridley; E Ron; E Weiderpass; L Mellemkjaer; A Ekbom; J H Olsen; J A Baron; J F Fraumeni
Journal:  Cancer Causes Control       Date:  2002-06       Impact factor: 2.506

7.  An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation.

Authors:  Erin K Maloney; Jennifer L McLaughlin; Nancy E Dagdigian; Lisa M Garrett; Katherine M Connors; Xiao-Mai Zhou; Walter A Blättler; Thomas Chittenden; Rajeeva Singh
Journal:  Cancer Res       Date:  2003-08-15       Impact factor: 12.701

8.  Prevention of cytokine-induced apoptosis by insulin-like growth factor-I is independent of cell adhesion molecules in HT29-D4 colon carcinoma cells-evidence for a NF-kappaB-dependent survival mechanism.

Authors:  F Garrouste; M Remacle-Bonnet; C Fauriat; J Marvaldi; J Luis; G Pommier
Journal:  Cell Death Differ       Date:  2002-07       Impact factor: 15.828

9.  A chimeric humanized single-chain antibody against the type I insulin-like growth factor (IGF) receptor renders breast cancer cells refractory to the mitogenic effects of IGF-I.

Authors:  Deepali Sachdev; Shu-Lian Li; Julie S Hartell; Yoko Fujita-Yamaguchi; Jeffrey S Miller; Douglas Yee
Journal:  Cancer Res       Date:  2003-02-01       Impact factor: 12.701

10.  IGF-1, IGF-2 and IGFBP-3 in prediagnostic serum: association with colorectal cancer in a cohort of Chinese men in Shanghai.

Authors:  N M Probst-Hensch; J M Yuan; F Z Stanczyk; Y T Gao; R K Ross; M C Yu
Journal:  Br J Cancer       Date:  2001-11-30       Impact factor: 7.640
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  20 in total

1.  Developmental stage determines estrogen receptor alpha expression and non-genomic mechanisms that control IGF-1 signaling and mammary proliferation in mice.

Authors:  Jie Tian; Thomas R Berton; Stephanie H Shirley; Isabel Lambertz; Irma B Gimenez-Conti; John DiGiovanni; Kenneth S Korach; Claudio J Conti; Robin Fuchs-Young
Journal:  J Clin Invest       Date:  2011-12-19       Impact factor: 14.808

2.  Association of insulin-like growth factor-I receptor polymorphism with colorectal cancer development.

Authors:  Noyko S Stanilov; Iliya A Karakolev; Tashko S Deliysky; Jovcho P Jovchev; Spaska A Stanilova
Journal:  Mol Biol Rep       Date:  2014-09-05       Impact factor: 2.316

3.  Therapeutic targeting of the phosphatidylinositol 3-kinase signaling pathway: novel targeted therapies and advances in the treatment of colorectal cancer.

Authors:  Ming Yu; William M Grady
Journal:  Therap Adv Gastroenterol       Date:  2012-09       Impact factor: 4.409

Review 4.  Molecular Targets in Biliary Carcinogenesis and Implications for Therapy.

Authors:  Tolutope Oyasiji; Jianliang Zhang; Boris Kuvshinoff; Renuka Iyer; Steven N Hochwald
Journal:  Oncologist       Date:  2015-05-29

Review 5.  Insulin-like growth factor: current concepts and new developments in cancer therapy.

Authors:  Erin R King; Kwong-Kwok Wong
Journal:  Recent Pat Anticancer Drug Discov       Date:  2012-01       Impact factor: 4.169

6.  Overcoming IGF1R/IR resistance through inhibition of MEK signaling in colorectal cancer models.

Authors:  Sara A Flanigan; Todd M Pitts; Timothy P Newton; Gillian N Kulikowski; Aik Choon Tan; Martine C McManus; Anna Spreafico; Maria I Kachaeva; Heather M Selby; John J Tentler; S Gail Eckhardt; Stephen Leong
Journal:  Clin Cancer Res       Date:  2013-09-17       Impact factor: 12.531

7.  Design of an insulin analog with enhanced receptor binding selectivity: rationale, structure, and therapeutic implications.

Authors:  Ming Zhao; Zhu-li Wan; Linda Whittaker; Bin Xu; Nelson B Phillips; Panayotis G Katsoyannis; Faramarz Ismail-Beigi; Jonathan Whittaker; Michael A Weiss
Journal:  J Biol Chem       Date:  2009-09-22       Impact factor: 5.157

8.  The emerging role of insulin-like growth factor 1 receptor (IGF1r) in gastrointestinal stromal tumors (GISTs).

Authors:  Maria A Pantaleo; Annalisa Astolfi; Margherita Nannini; Guido Biasco
Journal:  J Transl Med       Date:  2010-11-15       Impact factor: 5.531

9.  Target identification of grape seed extract in colorectal cancer using drug affinity responsive target stability (DARTS) technique: role of endoplasmic reticulum stress response proteins.

Authors:  Molly M Derry; Ranganatha R Somasagara; Komal Raina; Sushil Kumar; Joe Gomez; Manisha Patel; Rajesh Agarwal; Chapla Agarwal
Journal:  Curr Cancer Drug Targets       Date:  2014       Impact factor: 3.428

10.  The IGF-1/IGF-1R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer.

Authors:  D A Lewis; J B Travers; A-K Somani; D F Spandau
Journal:  Oncogene       Date:  2009-12-07       Impact factor: 9.867
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