Literature DB >> 17977064

Electrophysiological evidence of doubly innervated branched muscle fibers in the human brachioradialis muscle.

Zoia C Lateva1, Kevin C McGill.   

Abstract

OBJECTIVE: Motor-unit action potentials (MUAPs) with unstable satellite (late-latency) components are found in EMG signals from the brachioradialis muscles of normal subjects. We analyzed the morphology and blocking behavior of these MUAPs to determine their anatomical origin.
METHODS: EMG signals were recorded from the brachioradialis muscles of 5 normal subjects during moderate-level isometric contractions. MUAP waveforms, discharge patterns, and blocking were determined using computer-aided EMG decomposition.
RESULTS: Twelve MUAPs with unstable satellite potentials were detected, always two together in the same signal. Each MUAP also had a second unstable component associated with its main spike. The blocking behavior of the unstable components depended on how close together the two MUAPs were when they discharged.
CONCLUSIONS: The latencies and blocking behavior indicate that the unstable components came from branched muscle fibers innervated by two different motoneurons. The satellite potentials were due to action potentials that traveled to the branching point along one branch and back along the other. The blockings were due to action-potential collisions when both motoneurons discharged close together in time. SIGNIFICANCE: Animal studies suggest that branched muscle fibers may be a normal characteristic of series-fibered muscles. This study adds to our understanding of these muscles in humans.

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Year:  2007        PMID: 17977064      PMCID: PMC2190294          DOI: 10.1016/j.clinph.2007.09.058

Source DB:  PubMed          Journal:  Clin Neurophysiol        ISSN: 1388-2457            Impact factor:   3.708


  23 in total

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Authors:  M Young; A Paul; J Rodda; M Duxson; P Sheard
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2.  Electrophysiological evidence of adult human skeletal muscle fibres with multiple endplates and polyneuronal innervation.

Authors:  Zoia C Lateva; Kevin C McGill; M Elise Johanson
Journal:  J Physiol       Date:  2002-10-15       Impact factor: 5.182

3.  Increased jitter and blocking in normal muscles due to doubly innervated muscle fibers.

Authors:  Zoia C Lateva; Kevin C McGill; M Elise Johanson
Journal:  Muscle Nerve       Date:  2003-10       Impact factor: 3.217

4.  Development of a mammalian series-fibered muscle.

Authors:  Angelika C Paul; Philip W Sheard; Marilyn J Duxson
Journal:  Anat Rec A Discov Mol Cell Evol Biol       Date:  2004-06

5.  Multifocal innervation and muscle length. A morphological study on the role of myo-myonal junctions, fiber branching and multiple innervation in muscles of different size and shape.

Authors:  W Zenker; D Snobl; R Boetschi
Journal:  Anat Embryol (Berl)       Date:  1990

6.  EMGLAB: an interactive EMG decomposition program.

Authors:  Kevin C McGill; Zoia C Lateva; Hamid R Marateb
Journal:  J Neurosci Methods       Date:  2005-07-18       Impact factor: 2.390

7.  Muscle fiber recovery functions studied with double pulse stimulation.

Authors:  M Mihelin; J V Trontelj; E Stålberg
Journal:  Muscle Nerve       Date:  1991-08       Impact factor: 3.217

8.  Implications of longitudinal muscle fibre splitting in neurogenic and myopathic disorders.

Authors:  M Swash; M S Schwartz
Journal:  J Neurol Neurosurg Psychiatry       Date:  1977-12       Impact factor: 10.154

9.  "Satellite potentials" and the duration of motor unit potentials in normal, neuropathic and myopathic muscles.

Authors:  A H Lang; V S Partanen
Journal:  J Neurol Sci       Date:  1976-04       Impact factor: 3.181

10.  Functionally complex muscles of the cat hindlimb. II. Mechanical and architectural heterogenity within the biceps femoris.

Authors:  C M Chanaud; C A Pratt; G E Loeb
Journal:  Exp Brain Res       Date:  1991       Impact factor: 1.972

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  1 in total

1.  The innervation and organization of motor units in a series-fibered human muscle: the brachioradialis.

Authors:  Zoia C Lateva; Kevin C McGill; M Elise Johanson
Journal:  J Appl Physiol (1985)       Date:  2010-04-01
  1 in total

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