| Literature DB >> 17973363 |
Jun Li1, Stephanie Y Chen, James J Li, Haixia Wang, Andres S Hernandez, Shiwei Tao, Christa M Musial, Fucheng Qu, Stephen Swartz, Sam T Chao, Neil Flynn, Brian J Murphy, Dorothy A Slusarchyk, Ramakrishna Seethala, Mujing Yan, Paul Sleph, Gary Grover, Mark A Smith, Blake Beehler, Leah Giupponi, Kenneth E Dickinson, Hongjian Zhang, William G Humphreys, Bharat P Patel, Mark Schwinden, Terry Stouch, Peter T W Cheng, Scott A Biller, William R Ewing, David Gordon, Jeffrey A Robl, Joseph A Tino.
Abstract
A tetrazole-based peptidomimetic 2 (BMS-317180) was discovered as a human growth hormone secretagogue (GHS). Compound 2 is a potent, novel, orally effective GHS that shows an excellent safety profile in preclinical studies. The compound was advanced into clinical development.Entities:
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Year: 2007 PMID： 17973363 DOI： 10.1021/jm7010595
Source DB: PubMed Journal: J Med Chem ISSN： 0022-2623 Impact factor: 7.446