Literature DB >> 17971953

Identification of protease substrates by combinatorial profiling on TentaGel beads.

Jacob Kofoed1, Jean-Louis Reymond.   

Abstract

Reacting a 65,536 member combinatorial library of octapeptides on TentaGel beads with various proteases followed by selective staining of the free amino termini at the reacted bead surface and sequence determination by amino acid analysis allowed the rapid identification of protease substrates.

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Year:  2007        PMID: 17971953     DOI: 10.1039/b713595e

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  Sensitive electrospray mass spectrometry analysis of one-bead-one-compound peptide libraries labeled by quaternary ammonium salts.

Authors:  Remigiusz Bąchor; Marzena Cydzik; Magdalena Rudowska; Alicja Kluczyk; Piotr Stefanowicz; Zbigniew Szewczuk
Journal:  Mol Divers       Date:  2012-06-28       Impact factor: 2.943

2.  Development of inductively coupled plasma-mass spectrometry-based protease assays.

Authors:  Urja S Lathia; Olga Ornatsky; Vladimir Baranov; Mark Nitz
Journal:  Anal Biochem       Date:  2009-11-11       Impact factor: 3.365

  2 in total

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