Literature DB >> 179709

Autogenous immunity to mouse mammary tumor virus in mouse strains of high and low mammary tumor incidence.

J N Ihle, L O Arthur, D L Fine.   

Abstract

Specific radioimmune precipitation assays were utilized to demonstrate the presence of precipitating antibodies to mouse mammary tumor virus (MMTV) in the high-spontaneous mammary tumor strains of mice: C3H/HeN+, GR/N, BALB/cfC3H, and C57BL/6 X C3H F1 (hereafter called B6C3F1). Antibody titers in C3H/HeN+ mice increased with age, with highest titers observed in tumor-bearing animals. MMTV-precipitating antibodies were not detectable by radioimmune precipitation assay in low-mammary tumor strains (AKR, BALB/c C57BL/6, and C3H/HeN-) but were detectable in MMTV-inoculated BALB/c mice. Appearance of antibodies preceded palpable tumor formation, and antibody titers were directly correlated to virus dose. Natural antibody to MMTV in C3H/HeN+ and B6C3F1 mice coexists with the murine leukemia virus natural antibody as determined by competition radioimmunoassays.

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Year:  1976        PMID： 179709

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


  10 in total

1.  Mice with spontaneous mammary tumors develop type-specific neutralizing and cytotoxic antibodies against the mouse mammary tumor virus envelope protein gp52.

Authors:  G Schochetman; L O Arthur; C W Long; R J Massey
Journal:  J Virol       Date:  1979-10       Impact factor: 5.103

Review 2.  Mouse mammary tumor virus and its interaction with the immune system.

Authors:  S R Ross
Journal:  Immunol Res       Date:  1998       Impact factor: 2.829

3.  Mouse mammary tumor virus (MMTV) infection in SWISS and RIII mice. Correlation between resistance to exogenous infection and anti-MMTV serum response.

Authors:  P Hainaut; D Vaira; C Francois; C M Calberg-Bacq
Journal:  Arch Virol       Date:  1990       Impact factor: 2.574

Review 4.  Natural and induced immunity to mouse mammary tumors and the mammary tumor virus (MuMTV).

Authors:  O Stutman
Journal:  Springer Semin Immunopathol       Date:  1982

5.  Monoclonal antibodies identify individual determinants on mouse mammary tumor virus glycoprotein gp52 with group, class, or type specificity.

Authors:  R J Massey; L O Arthur; R C Nowinski; G Schochetman
Journal:  J Virol       Date:  1980-06       Impact factor: 5.103

6.  C3H/HeN mammary tumor-bearing mice develop type-specific neutralizing antibodies and group-specific precipitating antibodies for the mouse mammary tumor virus.

Authors:  R Massey; L O Arthur; C W Long; G Schochetman
Journal:  J Virol       Date:  1980-01       Impact factor: 5.103

7.  Virus-specific cytotoxic activity to mammary tumor cells of sera from normal and tumor-bearing mice with inhibition at low dilutions.

Authors:  P Creemers
Journal:  Infect Immun       Date:  1981-04       Impact factor: 3.441

8.  Effect of the age-related immune depression induced by MTV on the in vivo growth of a mammary carcinoma.

Authors:  A Tagliabue; W Luini; G De Vito; D Boraschi
Journal:  Br J Cancer       Date:  1981-09       Impact factor: 7.640

9.  Membrane fluidity, capping of cell-surface antigens and immune response in mouse leukaemia cells.

Authors:  J Hilgers; P J van der Sluis; W J van Blitterswijk; P Emmelot
Journal:  Br J Cancer       Date:  1978-03       Impact factor: 7.640

10.  Identification and characterization of a mouse mammary tumor virus protein uniquely expressed on the surface of BALB/cV mammary tumor cells.

Authors:  B L Slagle; J S Butel
Journal:  Virology       Date:  1985-05       Impact factor: 3.616
  10 in total

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