Literature DB >> 17969412

[Use of endotracheobronchial surgery in conjunction with radiochemotherapy for advanced non-small lung cancer].

A I Arsen'ev, S V Kanaev, A S Barchuk, Ia O Vedenin, V N Klitenko, M L Gel'fond, A V Shulenov, Iu A Morozova, A A Barchuk, S A Tarkov.   

Abstract

The paper deals with data on 191 endotracheobronchial surgeries (ETBS) in 153 patients with advanced non-small lung cancer involving breath obstruction (stage IIb--13.7%, III--71.9%, IV--14.4%). Difficulty in breathing either subsided or decreased significantly immediately after surgery. When followed by radiochemotherapy, ETBS was followed by survival median (over 14 months), both until tumor progression and during relapse-free survival. Complications were infrequent (8.5%); there was no lethality. End results were improved due to use of photodynamic therapy at the closing stage of treatment which pushed survival median to 17 months. In 11 cases (7.2%), combination of ETBS and radiotherapy rendered tumor operable; after radical surgery, survival median rose to 23 months, relapse-free survival--20 months. Postoperative radiotherapy was followed by 23.5 and 22 months of survival respectively. Hence, ETBS alone or carried out in conjunction with radiochemotherapy significantly improved (by 30-50%) quality of life in patients with advanced non-small lung cancer.

Entities:  

Mesh:

Year:  2007        PMID: 17969412

Source DB:  PubMed          Journal:  Vopr Onkol        ISSN: 0507-3758


  3 in total

1.  Photodynamic therapy for the treatment of non-small cell lung cancer.

Authors:  Charles B Simone; Joseph S Friedberg; Eli Glatstein; James P Stevenson; Daniel H Sterman; Stephen M Hahn; Keith A Cengel
Journal:  J Thorac Dis       Date:  2012-02       Impact factor: 2.895

Review 2.  Photodynamic therapy for lung cancer and malignant pleural mesothelioma.

Authors:  Charles B Simone; Keith A Cengel
Journal:  Semin Oncol       Date:  2014-10-07       Impact factor: 4.929

Review 3.  Photodynamic Therapy of Non-Small Cell Lung Cancer. Narrative Review and Future Directions.

Authors:  Gal Shafirstein; Athar Battoo; Kassem Harris; Heinz Baumann; Sandra O Gollnick; Joerg Lindenmann; Chukwumere E Nwogu
Journal:  Ann Am Thorac Soc       Date:  2016-02
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.