Literature DB >> 17969401

[Phase II clinical trial of neoadjuvant hormone therapy in comparison with chemotherapy of patients with breast cancer].

V F Semiglazov, V V Semiglazov, G A Dashian, E K Zhil'tsova, V G Ivanov, A A Bozhok, E E Tonuzov, R M Paltuev, O A Mel'nikova, A A Klettsel', P V Krivorot'ko, R V Donskikh, I A Kochetova, A O Damenia, K Iu Zernov, D A Voskresenskiĭ, L M Bershteĭn.   

Abstract

Data are presented on a randomized study (stage II) which was undertaken to assess the efficacy of neoadjuvant chemotherapy (doxorubicin+paclitaxel) vis-a-vis endocrine therapy with aromatase inhibitors (anastrazole or exemestane) in postmenopausal women with ER-positive and/or PgR-positive tumors. Preoperative neoadjuvant chemotherapy was well tolerated and showed similar rates of overall response as compared with the latter regimen.

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Year:  2007        PMID: 17969401

Source DB:  PubMed          Journal:  Vopr Onkol        ISSN: 0507-3758


  1 in total

Review 1.  Neoadjuvant Model as a Platform for Research in Breast Cancer and Novel Targets under Development in this Field.

Authors:  Santiago Escrivá-de-Romaní; Miriam Arumí; Esther Zamora; Meritxell Bellet
Journal:  Breast Care (Basel)       Date:  2018-08-14       Impact factor: 2.860

  1 in total

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