Literature DB >> 17968199

Analgesic efficacy of orodispersible paracetamol in patients admitted to the emergency department with an osteoarticular injury.

Alain Viallon1, Olivier Marjollet, Pantéa Guyomarch, Florianne Robert, Cristophe Berger, Stéphane Guyomarch, Marie Louise Navez, Jean-Claude Bertrand.   

Abstract

INTRODUCTION: Acute pain still persists in patients under treatment after admission to emergency departments (ED). The objective of this study was to determine the efficacy of 1 g of paracetamol in patients presenting an osteoarticular injury.
MATERIALS AND METHODS: This prospective study included all patients admitted to the ED with an osteoarticular injury and a pain score above 30 on the visual analogue scale (VAS). Patients were selected on admission by the reception nurse and given paracetamol within 5 min of admission. VAS scores were recorded 30 and 60 min after admission. On discharge from the ED, the patients underwent a further VAS assessment and were asked a question about pain relief (yes/no answer). The primary endpoint was the VAS score at 60 min. The secondary endpoint was the pain relief expressed by the patient on discharge from the ED.
RESULTS: Five hundred and seventy-one patients were included. The median stay in the ED was 90 min (75-120 min). The diagnoses at discharge were sprain or dislocation (ankle, knee, and wrist) for 287 patients, fracture for 102 patients, and other injury for 182 patients. In 69% of the patients, the injured limb was immobilized. The median VAS score on admission was 57. A significant difference was seen between the median VAS on admission and at 1 h after admission (57+/-18 vs. 30+/-18; P<0.0001), and between the median VAS score at admission and the score at discharge from the ED (57+/-18 vs. 26+/-18, P<0.0001). Finally, 81% of the patients expressed pain relief. On discharge from the ED, a gain of 20 mm on the VAS had a positive predictive value of 93% [area under curve (AUC): 89; CI: 86-92; P=0.001], for the endpoint 'patients stating pain relief'.
CONCLUSION: A simple and easily applicable protocol of pain management permits the achievement of satisfactory analgesia during a patient's stay in the ED.

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Year:  2007        PMID: 17968199     DOI: 10.1097/MEJ.0b013e3282703606

Source DB:  PubMed          Journal:  Eur J Emerg Med        ISSN: 0969-9546            Impact factor:   2.799


  4 in total

1.  Multimodal oral analgesia for non-severe trauma patients: evaluation of a triage-nurse directed protocol combining methoxyflurane, paracetamol and oxycodone.

Authors:  Damien Viglino; Nicolas Termoz Masson; Agnès Verdetti; Flore Champel; Cédric Falcon; Alexis Mouthon; Prudence Mabiala Makele; Roselyne Collomb Muret; Caroline Maindet Dominici; Maxime Maignan
Journal:  Intern Emerg Med       Date:  2019-07-09       Impact factor: 3.397

Review 2.  Exploring Opioid-Sparing Multimodal Analgesia Options in Trauma: A Nursing Perspective.

Authors:  Denise Sullivan; Mary Lyons; Robert Montgomery; Ann Quinlan-Colwell
Journal:  J Trauma Nurs       Date:  2016 Nov/Dec       Impact factor: 1.010

3.  Intravenous Acetaminophen vs. Ketorolac in Terms of Pain Management in Prehospital Emergency Services: A Randomized Clinical Trial.

Authors:  Babak Mahshidfar; Mahdi Rezai; Saeed Abbasi; Davood Farsi; Peyman Hafezimoghadam; Mani Mofidi; Ramin Almasi; Shaqayeq Khosravi
Journal:  Adv J Emerg Med       Date:  2019-05-08

Review 4.  Assessment and Early Management of Pain in Hip Fractures: The Impact of Paracetamol.

Authors:  Ján Dixon; Fiona Ashton; Paul Baker; Karl Charlton; Charlotte Bates; William Eardley
Journal:  Geriatr Orthop Surg Rehabil       Date:  2018-10-25
  4 in total

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