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Literature DB >> 17968145

High frequency of BRCA1/2 and p53 somatic inactivation in sporadic ovarian cancer.

Michal Zikan¹, Marketa Janatova, David Pavlista, Petr Pohlreich.

Abstract

Entities: Disease Gene

Mesh：

Year: 2007 PMID： 17968145 DOI： 10.1007/s12041-007-0022-y

Source DB: PubMed Journal: J Genet ISSN： 0022-1333 Impact factor: 1.166

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13 in total

1. Inactivation of BRCA1 and BRCA2 in ovarian cancer.

Authors: Jeffrey L Hilton; John P Geisler; Jennifer A Rathe; Melanie A Hattermann-Zogg; Barry DeYoung; Richard E Buller
Journal: J Natl Cancer Inst Date: 2002-09-18 Impact factor: 13.506

Review 2. Epigenetics in cancer: implications for early detection and prevention.

Authors: Mukesh Verma; Sudhir Srivastava
Journal: Lancet Oncol Date: 2002-12 Impact factor: 41.316

3. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.

Authors: M Esteller; J M Silva; G Dominguez; F Bonilla; X Matias-Guiu; E Lerma; E Bussaglia; J Prat; I C Harkes; E A Repasky; E Gabrielson; M Schutte; S B Baylin; J G Herman
Journal: J Natl Cancer Inst Date: 2000-04-05 Impact factor: 13.506

4. Loss of heterozygosity on chromosome 13q12-q14, BRCA-2 mutations and lack of BRCA-2 promoter hypermethylation in sporadic epithelial ovarian tumors.

Authors: E Gras; J Cortes; O Diez; C Alonso; X Matias-Guiu; M Baiget; J Prat
Journal: Cancer Date: 2001-08-15 Impact factor: 6.860

5. Promoter hypermethylation and post-transcriptional mechanisms for reduced BRCA1 immunoreactivity in sporadic human breast cancers.

Authors: Kazuaki Miyamoto; Takashi Fukutomi; Kiyoshi Asada; Kuniko Wakazono; Hitoshi Tsuda; Toshimasa Asahara; Takashi Sugimura; Toshikazu Ushijima
Journal: Jpn J Clin Oncol Date: 2002-03 Impact factor: 3.019

6. Frequency of BRCA1 dysfunction in ovarian cancer.

Authors: John P Geisler; Melanie A Hatterman-Zogg; Jennifer A Rathe; Richard E Buller
Journal: J Natl Cancer Inst Date: 2002-01-02 Impact factor: 13.506

7. Mutations of the BRCA2 gene in ovarian carcinomas.

Authors: H Takahashi; H C Chiu; C A Bandera; K Behbakht; P C Liu; F J Couch; B L Weber; V A LiVolsi; M Furusato; B A Rebane; A Cardonick; I Benjamin; M A Morgan; S A King; J J Mikuta; S C Rubin; J Boyd
Journal: Cancer Res Date: 1996-06-15 Impact factor: 12.701

High frequency of BRCA1/2 and p53 somatic inactivation in sporadic ovarian cancer.

1. Inactivation of BRCA1 and BRCA2 in ovarian cancer.

Review 2. Epigenetics in cancer: implications for early detection and prevention.

3. Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.

4. Loss of heterozygosity on chromosome 13q12-q14, BRCA-2 mutations and lack of BRCA-2 promoter hypermethylation in sporadic epithelial ovarian tumors.

5. Promoter hypermethylation and post-transcriptional mechanisms for reduced BRCA1 immunoreactivity in sporadic human breast cancers.

6. Frequency of BRCA1 dysfunction in ovarian cancer.

7. Mutations of the BRCA2 gene in ovarian carcinomas.

8. Mutational analysis of the BRCA1 gene in 30 Czech ovarian cancer patients.

9. Detection of the most frequent mutations in BRCA1 gene on polyacrylamide gels containing Spreadex Polymer NAB.

Review 10. The role of the breast cancer susceptibility gene 1 (BRCA1) in sporadic epithelial ovarian cancer.

Review 1. Fanconi anaemia: from a monogenic disease to sporadic cancer.

Review 2. Pathway modulations and epigenetic alterations in ovarian tumorbiogenesis.

3. Physiological modulation of endogenous BRCA1 p220 abundance suppresses DNA damage during the cell cycle.