| Literature DB >> 17967537 |
Alireza Foroumadi1, Alireza Samzadeh-Kermani, Saeed Emami, Gholamreza Dehghan, Maedeh Sorkhi, Fatemeh Arabsorkhi, Mahmoud Reza Heidari, Mohammad Abdollahi, Abbas Shafiee.
Abstract
A series of 3-benzylidene-7-alkoxychroman-4-one derivatives were synthesized and evaluated for their antioxidant activities. The antioxidant activity was assessed using three methods, namely, 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging, ferric reducing antioxidant power (FRAP), and thiobarbituric acid reactive substances (TBARS) assays. 3-Benzylidene-7-alkoxychroman-4-one derivatives bearing catecholic group on benzylidene moiety exhibited excellent antioxidant activity. Compounds having catechol moiety exhibited potent antioxidant activities in all tested methods and they were more active than the reference drug, Trolox.Entities:
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Year: 2007 PMID： 17967537 DOI： 10.1016/j.bmcl.2007.10.034
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823