Literature DB >> 17967034

Synthesis of chiral 3-substituted indanones via an enantioselective reductive-Heck reaction.

Ana Minatti1, Xiaolai Zheng, Stephen L Buchwald.   

Abstract

An efficient intramolecular palladium-catalyzed, asymmetric reductive-Heck reaction has been developed, which allowed for the synthesis of either enantiomerically enriched 3-substituted indanones or alpha-exo-methylene indanones depending on the base used.

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Year:  2007        PMID： 17967034     DOI： 10.1021/jo701741y

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  9 in total

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3.  Enantioselective photochemistry through Lewis acid-catalyzed triplet energy transfer.

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Journal:  Science       Date:  2016-12-16       Impact factor: 47.728

4.  Palladium-Catalyzed Reductive Heck Coupling of Alkenes.

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Journal:  Trends Chem       Date:  2019-06-20

5.  Palladium catalyzed reductive Heck coupling and its application in total synthesis of (-)-17-nor-excelsinidine.

Authors:  Lisi Yuan; Linrong Chen; Xiaoxiao Yan; Kun Gao; Xiaolei Wang
Journal:  RSC Adv       Date:  2021-02-17       Impact factor: 3.361

6.  Efficient kinetic resolution in the asymmetric transfer hydrogenation of 3-aryl-indanones: applications to a short synthesis of (+)-indatraline and a formal synthesis of (R)-tolterodine.

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Journal:  RSC Adv       Date:  2021-06-30       Impact factor: 3.361

7.  Study on the synthesis of the cyclopenta[f]indole core of raputindole A.

Authors:  Nils Marsch; Mario Kock; Thomas Lindel
Journal:  Beilstein J Org Chem       Date:  2016-02-23       Impact factor: 2.883

8.  Enantioselective synthesis of quaternary 3,4-dihydroisoquinolinones via Heck carbonylation reactions: development and application to the synthesis of Minalrestat analogues.

Authors:  Cang Cheng; Bin Wan; Bo Zhou; Yichao Gu; Yanghui Zhang
Journal:  Chem Sci       Date:  2019-09-03       Impact factor: 9.825

9.  Regioselective cobalt(II)-catalyzed [2 + 3] cycloaddition reaction of fluoroalkylated alkynes with 2-formylphenylboronic acids: easy access to 2-fluoroalkylated indenols.

Authors:  Tatsuya Kumon; Miroku Shimada; Jianyan Wu; Shigeyuki Yamada; Tsutomu Konno
Journal:  Beilstein J Org Chem       Date:  2020-09-04       Impact factor: 2.883
  9 in total

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