Literature DB >> 17966419

Roles of YopN, LcrG and LcrV in controlling Yops secretion by Yersinia pestis.

Mohamad A Hamad1, Matthew L Nilles.   

Abstract

Control of Yops secretion in pathogenic Yersinia is achieved at several levels. These levels likely include transcriptional, post-transcriptional, translational and secretional controls. Secretion control appears to be mediated by two pathways. One pathway involves YopN and proteins that interact with YopN. The second pathway consists of LcrG and its interaction with LcrV. LcrV is a postive regulator of Yops secretion that exerts control over Yops secretion by negating the secretion blocking role of LcrG. However, the intersection of these two control pathways is not understood. Recent work has allowed the development of a speculative model that brings YopN-mediated and LcrG-LcrV-mediated control together in the context of the ability of the needle complex to respond to Ca2+.

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Year:  2007        PMID： 17966419     DOI： 10.1007/978-0-387-72124-8_20

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  10 in total

Review 1.  Protein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant- and animal-pathogenic bacteria.

Authors:  Daniela Büttner
Journal:  Microbiol Mol Biol Rev       Date:  2012-06       Impact factor: 11.056

2.  An Interaction between the Inner Rod Protein YscI and the Needle Protein YscF Is Required to Assemble the Needle Structure of the Yersinia Type Three Secretion System.

Authors:  Shi-Yang Cao; Wan-Bin Liu; Ya-Fang Tan; Hui-Ying Yang; Ting-Ting Zhang; Tong Wang; Xiao-Yi Wang; Ya-Jun Song; Rui-Fu Yang; Zong-Min Du
Journal:  J Biol Chem       Date:  2017-02-14       Impact factor: 5.157

3.  A mutant with aberrant extracellular LcrV-YscF interactions fails to form pores and translocate Yop effector proteins but retains the ability to trigger Yop secretion in response to host cell contact.

Authors:  Dana E Harmon; Julia L Murphy; Alison J Davis; Joan Mecsas
Journal:  J Bacteriol       Date:  2013-03-08       Impact factor: 3.490

4.  Impact of host membrane pore formation by the Yersinia pseudotuberculosis type III secretion system on the macrophage innate immune response.

Authors:  Laura Kwuan; Walter Adams; Victoria Auerbuch
Journal:  Infect Immun       Date:  2013-01-07       Impact factor: 3.441

5.  Characterization of an F1 deletion mutant of Yersinia pestis CO92, pathogenic role of F1 antigen in bubonic and pneumonic plague, and evaluation of sensitivity and specificity of F1 antigen capture-based dipsticks.

Authors:  Jian Sha; Janice J Endsley; Michelle L Kirtley; Sheri M Foltz; Matthew B Huante; Tatiana E Erova; Elena V Kozlova; Vsevolod L Popov; Linsey A Yeager; Irina V Zudina; Vladimir L Motin; Johnny W Peterson; Kristin L DeBord; Ashok K Chopra
Journal:  J Clin Microbiol       Date:  2011-03-02       Impact factor: 5.948

Review 6.  Structure and biophysics of type III secretion in bacteria.

Authors:  Srirupa Chatterjee; Sukanya Chaudhury; Andrew C McShan; Kawaljit Kaur; Roberto N De Guzman
Journal:  Biochemistry       Date:  2013-04-05       Impact factor: 3.162

7.  The LcrG Tip Chaperone Protein of the Yersinia pestis Type III Secretion System Is Partially Folded.

Authors:  Sukanya Chaudhury; Clarice de Azevedo Souza; Gregory V Plano; Roberto N De Guzman
Journal:  J Mol Biol       Date:  2015-08-07       Impact factor: 5.469

8.  Modified needle-tip PcrV proteins reveal distinct phenotypes relevant to the control of type III secretion and intoxication by Pseudomonas aeruginosa.

Authors:  Hiromi Sato; Meredith L Hunt; Joshua J Weiner; Andrew T Hansen; Dara W Frank
Journal:  PLoS One       Date:  2011-03-29       Impact factor: 3.240

9.  The Ruler Protein EscP of the Enteropathogenic Escherichia coli Type III Secretion System Is Involved in Calcium Sensing and Secretion Hierarchy Regulation by Interacting with the Gatekeeper Protein SepL.

Authors:  Lihi Shaulov; Jenia Gershberg; Wanyin Deng; B Brett Finlay; Neta Sal-Man
Journal:  MBio       Date:  2017-01-03       Impact factor: 7.867

Review 10.  Regulation of the Yersinia type III secretion system: traffic control.

Authors:  Rebecca S Dewoody; Peter M Merritt; Melanie M Marketon
Journal:  Front Cell Infect Microbiol       Date:  2013-02-06       Impact factor: 5.293
  10 in total

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