Literature DB >> 17965966

Natriuretic peptides in cardiovascular diseases.

Mariusz Piechota1, Maciej Banach, Anna Jacoń, Jacek Rysz.   

Abstract

The natriuretic peptide family comprises atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), C-type natriuretic peptide (CNP), dendroaspis natriuretic peptide (DNP), and urodilatin. The activities of natriuretic peptides and endothelins are strictly associated with each other. ANP and BNP inhibit endothelin-1 (ET-1) production. ET-1 stimulates natriuretic peptide synthesis. All natriuretic peptides are synthesized from polypeptide precursors. Changes in natriuretic peptides and endothelin release were observed in many cardiovascular diseases: e.g. chronic heart failure, left ventricular dysfunction and coronary artery disease.

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Year:  2008        PMID： 17965966      PMCID： PMC6275881          DOI： 10.2478/s11658-007-0046-6

Source DB:  PubMed          Journal:  Cell Mol Biol Lett        ISSN： 1425-8153            Impact factor:   5.787


  119 in total

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