Literature DB >> 17963768

Misoprostol: pharmacokinetic profiles, effects on the uterus and side-effects.

O S Tang1, K Gemzell-Danielsson, P C Ho.   

Abstract

Misoprostol, a synthetic prostaglandin E1 analogue, is commonly used for medical abortion, cervical priming, the management of miscarriage, induction of labor and the management of postpartum hemorrhage. It can be given orally, vaginally, sublingually, buccally or rectally. Studies of misoprostol's pharmacokinetics and effects on uterine activity have demonstrated the properties of the drug after various routes of administration. These studies can help to discover the optimal dose and route of administration of misoprostol for individual clinical applications. Misoprostol is a safe drug but serious complications and teratogenicity can occur with unsupervised use.

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Year:  2007        PMID： 17963768     DOI： 10.1016/j.ijgo.2007.09.004

Source DB:  PubMed          Journal:  Int J Gynaecol Obstet        ISSN： 0020-7292            Impact factor:   3.561


  39 in total

1.  Sublingual misoprostol to reduce blood loss at cesarean delivery.

Authors:  Atul Kumar Sood; Sanjay Singh
Journal:  J Obstet Gynaecol India       Date:  2012-06-01

2.  Medical termination of pregnancy in cynomolgus macaques.

Authors:  Elizabeth Micks; Taylor Shekell; Jessica Stanley; Mary Zelinski; Lauren Martin; Serena Riefenberg; Tiffany Adevai; Jeffrey Jensen
Journal:  J Med Primatol       Date:  2012-10-18       Impact factor: 0.667

3.  Uses of misoprostol in obstetrics and gynecology.

Authors:  Rebecca Allen; Barbara M O'Brien
Journal:  Rev Obstet Gynecol       Date:  2009

Review 4.  Misoprostol to reduce intraoperative and postoperative hemorrhage during cesarean delivery: a systematic review and metaanalysis.

Authors:  Agustín Conde-Agudelo; Aníbal Nieto; Anyeli Rosas-Bermudez; Roberto Romero
Journal:  Am J Obstet Gynecol       Date:  2013-03-15       Impact factor: 8.661

5.  Misoprostol for termination of pregnancy-can it precipitate a seizure in a well controlled secondary epileptic tuberculoma patient?

Authors:  Pushparaj Mohanraj; Pradeep Kumar Garg; Deepa Maheswari Narasimalu
Journal:  J Turk Ger Gynecol Assoc       Date:  2010-03-01

6.  Home-Based Extended Low-Dose Oral Misoprostol in Management of First-Trimester Pregnancy Loss in Low-Resource Communities: A Randomized Trial.

Authors:  Ayman H Shaamash; E A Khlifah; A M Esmail; Sh G Abdelmonem
Journal:  J Obstet Gynaecol India       Date:  2019-06-26

7.  Mifepristone Followed by Misoprostol or Ethacridine Lactate and Oxytocin for Second Trimester Abortion: A Randomized Trial.

Authors:  Vatsla Dadhwal; Sita Garimella; Kavita Khoiwal; K Aparna Sharma; Vanamail Perumal; Dipika Deka
Journal:  Eurasian J Med       Date:  2019-08-19

8.  Randomised Controlled Trial of Sublingual and Rectal Misoprostol in the Prevention of Primary Postpartum Haemorrhage in a Resource-Limited Community.

Authors:  Jacob Olumuyiwa Awoleke; Benedict Tolulope Adeyanju; Adebayo Adeniyi; Olusola Peter Aduloju; Babatunde Ajayi Olofinbiyi
Journal:  J Obstet Gynaecol India       Date:  2020-06-29

9.  Endometrial thickness following early miscarriage in IVF patients - is there a preferred management approach?

Authors:  Gilad Karavani; Heli Alexandroni; Daniel Sheinin; Uri P Dior; Alex Simon; Assaf Ben-Meir; Benjamin Reubinoff
Journal:  Reprod Biol Endocrinol       Date:  2021-06-22       Impact factor: 5.211

10.  Misoprostol-induced Coronary Vasospasm Complicated by Takotsubo Cardiomyopathy and Cardiac Arrest.

Authors:  Parminder Kaur; Melvin Santana; Balraj Singh; Anuraag Sah; Raja Pullatt; Fayez Shamoon
Journal:  Eur J Case Rep Intern Med       Date:  2021-06-23
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