| Literature DB >> 17963462 |
Rami B Ibrahim1, Chin Liu, Simon M Cronin, Bridgette C Murphy, Raymond Cha, Paul Swerdlow, David J Edwards.
Abstract
Contrary to the literature about drug removal during hemodialysis, data regarding drug removal during plasmapheresis are sparse. Over the last 40 years, approximately 70 publications-mostly case reports of overdoses-have described the effects of plasmapheresis on pharmaceutical agents. Important issues are drug extraction during plasma exchange with chemotherapy, as well as drug classes such as antiinfectives, anticoagulants, antiepileptics, cardiovascular agents, and immunosuppressants. Other considerations are the merits and pitfalls of the different methods used in published reports and recommendations for future pharmacokinetic studies in this field.Mesh：
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Year: 2007 PMID： 17963462 DOI： 10.1592/phco.27.11.1529
Source DB: PubMed Journal: Pharmacotherapy ISSN： 0277-0008 Impact factor: 4.705