Literature DB >> 17962969

Squamous cell carcinoma of the nasal columella: a retrospective study of 66 cases from the GETTEC.

Olivier Choussy1, Emmanuel Babin, Stéphane Temam, Alain Cosmidis, Pierre-Olivier Vedrine, Dominique De Raucourt, Jérôme Sarini, Jean-Pierre Bessede, Pierre-Yves Lienhardt, Danièle Dehesdin.   

Abstract

Squamous cell carcinoma of the nasal columella (SCCNC) is a rare disease. We aimed to define a strategy for the diagnosis and management of nasal columella squamous cell carcinoma. Medical records of 66 patients presenting with columella squamous cell carcinoma in nine French hospitals, from 1980 to 2003, were evaluated to determine the clinical characteristics and current treatment of the disease. Mean age was 69 years. The sex ratio was one female for three males. Majority of the lesions were T1 N0 according to the classification international union against cancer. Patients underwent one of the three treatments: surgery alone for the T1 lesions, radiotherapy for tumors of T2-T3 and combined (surgery and radiotherapy) for T4 lesions. The 5-year Kaplan-Meier survival test was 39% and no difference was found between the therapeutic groups. Thirty-five (53%) tumor recurrences were observed with a median time of 43 months. As regards TNM classification and treatment, no significant difference between the two groups disease free/recurrence was found. Prognosis of early lesions was considered better than the advanced lesions. SCCNC is difficult to manage and has a poor prognosis. No therapeutic solution has yet been confirmed in the treatment of this pathology.

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Year:  2007        PMID: 17962969     DOI: 10.1007/s00405-007-0503-x

Source DB:  PubMed          Journal:  Eur Arch Otorhinolaryngol        ISSN: 0937-4477            Impact factor:   2.503


  30 in total

1.  Neck dissection classification update: revisions proposed by the American Head and Neck Society and the American Academy of Otolaryngology-Head and Neck Surgery.

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Authors:  M Poulsen; S Turner
Journal:  Int J Radiat Oncol Biol Phys       Date:  1993-09-30       Impact factor: 7.038

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Authors:  S Vadivel; A Bosch; Z Frias; W L Caldwell
Journal:  Wis Med J       Date:  1978-09

7.  Squamous cell carcinoma of the anterior nasal cavity: a dual institution review.

Authors:  R A Fornelli; F G Fedok; E P Wilson; S M Rodman
Journal:  Otolaryngol Head Neck Surg       Date:  2000-09       Impact factor: 3.497

8.  Tumors of the nasal columella treated by Mohs micrographic surgery.

Authors:  H A Oriba; S N Snow
Journal:  Laryngoscope       Date:  1997-12       Impact factor: 3.325

9.  Reconstruction of columella, membranous septum, and upper lip in a single stage operation.

Authors:  Hayati Akbaş; Mustafa Keskin; Ethem Güneren; Lütfi Eroğlu; Ahmet Demir
Journal:  Br J Plast Surg       Date:  2003-04

10.  Carcinoma of the nasal septum: experience with 85 cases.

Authors:  C W Beatty; B W Pearson; E B Kern
Journal:  Otolaryngol Head Neck Surg       Date:  1982 Jan-Feb       Impact factor: 3.497

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