Literature DB >> 17962785

Synthesis and antidepressant evaluation of three para-benzoquinone mono-oximes and their oxy derivatives.

Damião Pergentino de Sousa1, Renata Rabelo Schefer, Ursula Brocksom, Timothy John Brocksom.   

Abstract

A series of three para-benzoquinone mono-oximes and four oxy-derivatives were prepared and tested for their antidepressant properties. The (4E) oxime of 2-isopropyl-5-methyl-para-benzoquinone (4) and the corresponding 2-diethylamino-ethyl derivative (10) present antidepressant activities and were slightly more potent than the reference standard.

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Year:  2006        PMID： 17962785      PMCID： PMC6148520          DOI： 10.3390/11020148

Source DB:  PubMed          Journal:  Molecules        ISSN： 1420-3049            Impact factor:   4.411


  7 in total

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Journal:  Nature       Date:  1977-04-21       Impact factor: 49.962

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6.  Synthesis of some 1-(2-naphthyl)-2-(imidazole-1-yl)ethanone oxime and oxime ether derivatives and their anticonvulsant and antimicrobial activities.

Authors:  A Karakurt; S Dalkara; M Ozalp; S Ozbey; E Kendi; J P Stables
Journal:  Eur J Med Chem       Date:  2001-05       Impact factor: 6.514

7.  2,3-Butanedione monoxime protects mice against the convulsant effect of picrotoxin by facilitating GABA-activated currents.

Authors:  T Brightman; J H Ye; E Ortiz-Jimenez; E J Flynn; W H Wu; J J McArdle
Journal:  Brain Res       Date:  1995-04-24       Impact factor: 3.252
  7 in total
  4 in total

1.  Oxime derivatives with larvicidal activity against Aedes aegypti L.

Authors:  Tamires Cardoso Lima; Sandra Regina Lima Santos; Marciana P Uliana; Roseli La Corte Santos; Timothy John Brocksom; Sócrates Cabral de Holanda Cavalcanti; Damião Pergentino de Sousa
Journal:  Parasitol Res       Date:  2015-05-09       Impact factor: 2.289

2.  Antinociceptive and anti-inflammatory effects of the monoterpene α,β-epoxy-carvone in mice.

Authors:  Marilene L da Rocha; Leandra E G Oliveira; Camila C M Patrício Santos; Damião P de Sousa; Reinaldo N de Almeida; Demetrius A M Araújo
Journal:  J Nat Med       Date:  2013-01-13       Impact factor: 2.343

3.  A convenient and eco-friendly cerium(III) chloride-catalysed synthesis of methoxime derivatives of aromatic aldehydes and ketones.

Authors:  Iván Cortés; Teodoro S Kaufman; Andrea B J Bracca
Journal:  R Soc Open Sci       Date:  2018-05-23       Impact factor: 2.963

4.  Conversion of natural aldehydes from Eucalyptus citriodora, Cymbopogon citratus, and Lippia multiflora into oximes: GC-MS and FT-IR analysis.

Authors:  Igor W Ouédraogo; Michael Boulvin; Robert Flammang; Pascal Gerbaux; Yvonne L Bonzi-Coulibaly
Journal:  Molecules       Date:  2009-08-31       Impact factor: 4.411
  4 in total

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