Literature DB >> 17961505

Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis.

Yann Wallez1, Philippe Huber.   

Abstract

Endothelial cells lining the vessel wall are connected by adherens, tight and gap junctions. These junctional complexes are related to those found at epithelial junctions but with notable changes in terms of specific molecules and organization. Endothelial junctional proteins play important roles in tissue integrity but also in vascular permeability, leukocyte extravasation and angiogenesis. In this review, we will focus on specific mechanisms of endothelial tight and adherens junctions.

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Year:  2007        PMID: 17961505     DOI: 10.1016/j.bbamem.2007.09.003

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  176 in total

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