Literature DB >> 17960144

Can inhaled prostacyclin stimulate surfactant in ELBW infants?

K Olmsted1, O Oluola, A Parthiban, T Raghuveer.   

Abstract

Respiratory distress syndrome (RDS) causes significant hypoxia in extremely low birth weight (ELBW) infants. We report an ELBW infant with RDS and pulmonary hypertension whose hypoxia did not respond to inhaled nitric oxide but improved with inhaled prostacyclin. We propose that inhaled prostacyclin alleviated the hypoxia by stimulating surfactant secretion.

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Year:  2007        PMID: 17960144     DOI: 10.1038/sj.jp.7211811

Source DB:  PubMed          Journal:  J Perinatol        ISSN: 0743-8346            Impact factor:   2.521


  5 in total

Review 1.  Pulmonary vasodilator therapy in the NICU: inhaled nitric oxide, sildenafil, and other pulmonary vasodilating agents.

Authors:  Nicolas F M Porta; Robin H Steinhorn
Journal:  Clin Perinatol       Date:  2012-03       Impact factor: 3.430

Review 2.  Pharmacotherapy for pulmonary hypertension.

Authors:  Robin H Steinhorn
Journal:  Pediatr Clin North Am       Date:  2012-08-26       Impact factor: 3.278

3.  Diagnosis and treatment of pulmonary hypertension in infancy.

Authors:  Robin H Steinhorn
Journal:  Early Hum Dev       Date:  2013-09-29       Impact factor: 2.079

Review 4.  A Review of Oxygen Physiology and Appropriate Management of Oxygen Levels in Premature Neonates.

Authors:  Allyson Kayton; Paula Timoney; Lyn Vargo; Jose A Perez
Journal:  Adv Neonatal Care       Date:  2018-04       Impact factor: 1.968

5.  Current Practices and Attitudes Regarding Use of Inhaled Nitric Oxide in the NICU: Results From a Survey of Members of the National Association of Neonatal Nurse Practitioners.

Authors:  Allyson Kayton; Paula Timoney; Lyn Vargo; Jose A Perez
Journal:  Adv Neonatal Care       Date:  2018-04       Impact factor: 1.968

  5 in total

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