Literature DB >> 17959381

Synthesis of novel neutrophil-specific imaging agents for Positron Emission Tomography (PET) imaging.

Yi Zhang1, Bijoy Kundu, Karen D Fairchild, Landon Locke, Stuart S Berr, Joel Linden, Dongfeng Pan.   

Abstract

A neutrophil-specific peptide, cinnamoyl-F(D)LF(D)LFK (cFLFLFK), was conjugated consecutively with a polyethylene glycol moiety (3.4K) and 2,2',2'',2'''-(1,4,7,10-tetraazacyclododecane-1,4,7,10-tetrayl)tetraacetic acid (DOTA) to form cFLFLFK-PEG-DOTA. After (64)Cu labeling, Positron Emission Tomography (PET) imaging was successfully able to detect mouse lung inflammation.

Entities:  

Mesh：

Substances：

Year:  2007        PMID： 17959381      PMCID： PMC2612577          DOI： 10.1016/j.bmcl.2007.10.013

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  6 in total

1.  Localization of radiolabeled chemotactic peptide at focal sites of Escherichia coli infection in rabbits: evidence for a receptor-specific mechanism.

Authors:  J W Babich; R G Tompkins; W Graham; S A Barrow; A J Fischman
Journal:  J Nucl Med       Date:  1997-08       Impact factor: 10.057

2.  Imaging inflammation with 99Tcm-labeled chemotactic peptides: analogues with reduced neutropenia.

Authors:  A Pollak; A E Goodbody; J R Ballinger; G S Duncan; L L Tran; R Dunn-Dufault; K Meghji; F Lau; T W Andrey; I Boxen; M Sumner-Smith
Journal:  Nucl Med Commun       Date:  1996-02       Impact factor: 1.690

3.  Tumor scanning with 67Ga citrate.

Authors:  C L Edwards; R L Hayes
Journal:  J Nucl Med       Date:  1969-02       Impact factor: 10.057

4.  Survey of radioactive agents for in vitro labeling of phagocytic leukocytes. I. Soluble agents.

Authors:  J G McAfee; M L Thakur
Journal:  J Nucl Med       Date:  1976-06       Impact factor: 10.057

5.  Pegylated Arg-Gly-Asp peptide: 64Cu labeling and PET imaging of brain tumor alphavbeta3-integrin expression.

Authors:  Xiaoyuan Chen; Yingping Hou; Michel Tohme; Ryan Park; Vazgen Khankaldyyan; Ignacio Gonzales-Gomez; James R Bading; Walter E Laug; Peter S Conti
Journal:  J Nucl Med       Date:  2004-10       Impact factor: 10.057

6.  Indium-111-labeled autologous leukocytes in man.

Authors:  M L Thakur; J P Lavender; R N Arnot; D J Silvester; A W Segal
Journal:  J Nucl Med       Date:  1977-10       Impact factor: 10.057
  6 in total
  8 in total

1.  Targeting of Formyl Peptide Receptor 2 for in vivo imaging of acute vascular inflammation.

Authors:  Tamara Boltersdorf; Junaid Ansari; Elena Y Senchenkova; Jieny Groeper; Denise Pajonczyk; Shantel A Vital; Gaganpreet Kaur; J Steve Alexander; Thomas Vogl; Ursula Rescher; Nicholas J Long; Felicity N E Gavins
Journal:  Theranostics       Date:  2020-05-17       Impact factor: 11.556

2.  A novel neutrophil-specific PET imaging agent: cFLFLFK-PEG-64Cu.

Authors:  Landon W Locke; Mahendra D Chordia; Yi Zhang; Bijoy Kundu; Dylan Kennedy; Jessica Landseadel; Li Xiao; Karen D Fairchild; Stuart S Berr; Joel Linden; Dongfeng Pan
Journal:  J Nucl Med       Date:  2009-04-16       Impact factor: 10.057

3.  PET imaging detection of macrophages with a formyl peptide receptor antagonist.

Authors:  Yi Zhang; Bijoy Kundu; Min Zhong; Tao Huang; Jing Li; Mahendra D Chordia; Mei-Hua Chen; Dongfeng Pan; Jiang He; Weibin Shi
Journal:  Nucl Med Biol       Date:  2014-12-06       Impact factor: 2.408

Review 4.  Recognition of Immune Response for the Early Diagnosis and Treatment of Osteoarthritis.

Authors:  Adrese M Kandahari; Xinlin Yang; Abhijit S Dighe; Dongfeng Pan; Quanjun Cui
Journal:  J Immunol Res       Date:  2015-05-03       Impact factor: 4.818

Review 5.  Development of copper based drugs, radiopharmaceuticals and medical materials.

Authors:  Paweł Szymański; Tomasz Frączek; Magdalena Markowicz; Elżbieta Mikiciuk-Olasik
Journal:  Biometals       Date:  2012-08-23       Impact factor: 2.949

Review 6.  Applications of in vivo imaging in the evaluation of the pathophysiology of viral and bacterial infections and in development of countermeasures to BSL3/4 pathogens.

Authors:  Thomas M Bocan; Rekha G Panchal; Sina Bavari
Journal:  Mol Imaging Biol       Date:  2015-02       Impact factor: 3.488

Review 7.  PET imaging of inflammation biomarkers.

Authors:  Chenxi Wu; Fang Li; Gang Niu; Xiaoyuan Chen
Journal:  Theranostics       Date:  2013-06-24       Impact factor: 11.556

Review 8.  Tuberculosis: Role of Nuclear Medicine and Molecular Imaging With Potential Impact of Neutrophil-Specific Tracers.

Authors:  Stuart More; Mohlopheni J Marakalala; Michael Sathekge
Journal:  Front Med (Lausanne)       Date:  2021-12-10
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.